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Recruiting EARLY_Phase 1 NCT05400967

NCT05400967 Diagnosis of Metastatic Tumors on 68Ga-FAPI PET-CT and Radioligand Therapy with 177Lu-EB-FAPI

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Clinical Trial Summary
NCT ID NCT05400967
Status Recruiting
Phase EARLY_Phase 1
Sponsor Peking Union Medical College Hospital
Condition 177Lu-EB-FAPI
Study Type INTERVENTIONAL
Enrollment 10 participants
Start Date 2022-01-01
Primary Completion 2025-01-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 80 Years
Study Type INTERVENTIONAL
Interventions
68Ga-FAPI for PET / CT scan and 177Lu-EB-FAPI for therapy

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 1 is the earliest stage of human testing — safety and dosage are the primary focus. Visits are frequent and medical supervision is intensive. You will be among the first people to receive this treatment.

This trial targets 10 participants in total. It began in 2022-01-01 with a primary completion date of 2025-01-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

FAP is a fibroblast activation protein and overexpressed in many tumor tissues. This study is intended to conduct preliminary clinical transformation and internal irradiation dosimetry research on 177Lu-EB-FAPI--a new 177Lu therapeutic drug modified by Evans Blue (EB) for the first time in the world.

Eligibility Criteria

Inclusion Criteria: * confirmed treated or untreated metastatic tumors patients; * 68Ga-FAPI PET/CT and 18F-FDG PET/CT within two weeks; * signed written consent. Exclusion Criteria: * pregnancy; * breastfeeding; * any medical condition that in the opinion of the investigator may significantly interfere with study compliance

Contact & Investigator

Central Contact

Zhaohui Zhu

✉ 13611093752@163.com

📞 86-13611093752

Frequently Asked Questions

Who can join the NCT05400967 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 80 Years, studying 177Lu-EB-FAPI. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT05400967 trial and what does that mean for participants?

Phase 1 trials are the first stage of human testing. The primary goal is to assess safety and determine appropriate dosage levels. Participants are closely monitored. These trials typically involve a small number of volunteers.

Is NCT05400967 currently recruiting?

Yes, NCT05400967 is actively recruiting participants. Contact the research team at 13611093752@163.com for enrollment information.

Where is the NCT05400967 trial being conducted?

This trial is being conducted at Beijing, China.

Who is sponsoring the NCT05400967 clinical trial?

NCT05400967 is sponsored by Peking Union Medical College Hospital. The trial plans to enroll 10 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology