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Recruiting NCT05278494

NCT05278494 Dextromethorphan for Treatment of Postoperative Pain

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Clinical Trial Summary
NCT ID NCT05278494
Status Recruiting
Phase
Sponsor Nathanael Heckmann
Condition Post-operative Pain
Study Type INTERVENTIONAL
Enrollment 160 participants
Start Date 2022-09-15
Primary Completion 2026-12-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Dextromethorphan HydrobromidePlacebo

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 160 participants in total. It began in 2022-09-15 with a primary completion date of 2026-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

A Randomized, Placebo-Controlled Study to Evaluate the Efficacy of Perioperative Dextromethorphan compared to Placebo for the Treatment of Postoperative Pain

Eligibility Criteria

Main Inclusion Criteria: * Patients Age ≥18 planning to undergo total knee arthroplasty * ASA classes I - III Main Exclusion Criteria: * BMI ≥ 35 * History opioid abuse * History of intractable vomiting after previous surgery

Contact & Investigator

Central Contact

Pui Yan, MS

✉ puiyan@med.usc.edu

📞 323-442-6984

Frequently Asked Questions

Who can join the NCT05278494 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Post-operative Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05278494 currently recruiting?

Yes, NCT05278494 is actively recruiting participants. Contact the research team at puiyan@med.usc.edu for enrollment information.

Where is the NCT05278494 trial being conducted?

This trial is being conducted at Los Angeles, United States.

Who is sponsoring the NCT05278494 clinical trial?

NCT05278494 is sponsored by Nathanael Heckmann. The trial plans to enroll 160 participants.

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