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Recruiting NCT06981494

Dexmedetomidine Versus Dexmedetomidine and Ketamine (Ketodex) in Ear and Nose Surgeries

Trial Parameters

Condition Ear and Nose Surgeries With Hypotensive Anaesthesia e.g FESS , MLS , TURBINECTOMY
Sponsor Sohag University
Study Type INTERVENTIONAL
Phase N/A
Enrollment 84
Sex ALL
Min Age 18 Years
Max Age 60 Years
Start Date 2025-02-05
Completion 2025-08-10
Interventions
DexmedetomidineDexmedetomidine and ketamine ( Ketodex )

Brief Summary

The study aims to compare the efficacy, safety and overall effectiveness of dexmedetomidine and dexmedtomidine and ketamine (ketodex) in achieving controlled hypotension during Ear and nose surgeries. \- Assessment the analgesic and sedative role of both drugs.

Eligibility Criteria

Inclusion Criteria * Age Range: Patients aged 18-60 years who are scheduled for elective Ear and nose surgeries requiring controlled hypotensive anesthesia. * ASA Classification: Patients classified as American Society of Anesthesiologists (ASA) physical status I or II. * Surgical Procedures: Individuals undergoing specific ear and nose surgeries where controlled hypotensive anesthesia is typically indicated. * Stable Cardiovascular Health: Patients with stable cardiovascular function, without significant history of uncontrolled hypertension , hypotension or ischaemic heart diseases. Exclusion Criteria * Severe Cardiovascular Conditions: Patients with severe cardiovascular diseases such as congestive heart failure, uncontrolled hypertension , arrhythmias or ischaemic heart diseases . * Any cardiac patients. * Respiratory Conditions: Individuals with significant respiratory conditions like chronic obstructive pulmonary disease (COPD) or severe asthma. * Drug Allergies: Patients with kno

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