NCT06380192 Developmental and Epileptic Encephalopathy of Genetic Etiology: Natural History Through Reuse of Clinical Data
| NCT ID | NCT06380192 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Imagine Institute |
| Condition | Developmental and Epileptic Encephalopathy |
| Study Type | OBSERVATIONAL |
| Enrollment | 400 participants |
| Start Date | 2024-10-31 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 400 participants in total. It began in 2024-10-31 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Developmental and Epileptic Encephalopathy (DEE) are a heterogeneous group of neurodevelopmental disorders linked to both epilepsy and its underlying etiology, independently of epileptiform activity. The creation of a database with retrospective follow-up of a large number of patients on a national scale will enable better knowledge of specific biomarkers, and thus a better classification and understanding of the natural evolution of DEE according to their etiology. This will enable better, more personalized therapeutic management of patients, depending on etiology and the presence or absence of these biomarkers. The investigators will also be able to draw up management recommendations, which are currently non-existent.
Eligibility Criteria
Inclusion Criteria: * Diagnosis of Developmental and Epileptic Encephalopathy * Registered with or benefiting from a social security scheme. Exclusion Criteria: * Opposition of the patient or his/her parents to the re-use of data in the context of this study * Person subject to a safeguard of justice measure
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06380192 clinical trial?
This trial is open to participants of all sexes, studying Developmental and Epileptic Encephalopathy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06380192 currently recruiting?
Yes, NCT06380192 is actively recruiting participants. Contact the research team at rima.nabbout@aphp.fr for enrollment information.
Where is the NCT06380192 trial being conducted?
This trial is being conducted at Amiens, France, Angers, France, Besançon, France, Bordeaux, France and 11 additional locations.
Who is sponsoring the NCT06380192 clinical trial?
NCT06380192 is sponsored by Imagine Institute. The trial plans to enroll 400 participants.