NCT06167928 Developing Allogeneic Musculoskeletal Therapies
| NCT ID | NCT06167928 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Keele University |
| Condition | Osteoarthritis |
| Study Type | OBSERVATIONAL |
| Enrollment | 325 participants |
| Start Date | 2018-10-08 |
| Primary Completion | 2028-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 325 participants in total. It began in 2018-10-08 with a primary completion date of 2028-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to analyse the cartilage and bone forming potential of cells isolated from the tissues of patients undergoing surgery for the treatment of polydactyly, hip dislocation and from other bio-banked cartilage tissues. The main question it aims to answer is: Which of the following tissues from polydactyly digit, iliac apophysis or other bio-banked cartilage produce better cartilage in vitro and in vivo? Participants receiving digit amputation surgery for treatment of polydactyly will be asked to donate the associated waste tissue whilst participants receiving surgery to treat a dislocated hip will be asked to donate an extra small piece of cartilage tissue (approximately 1 gram) from the iliac apophysis. Other tissues for the study will be obtained from those donated to biobanks.
Eligibility Criteria
Inclusion Criteria: For juvenile/infant donors: * Parents/guardians being able to provide signed and dated informed consent form. * Scheduled for one of the following surgical treatments: Digit amputations due to polydactyly. Surgery to treat dislocated hips. For biobank/NHSBT donors * Informed consent via consenting institution. Exclusion Criteria: * Parents/guardians not understanding the Patient Information Sheet
Contact & Investigator
Karina T Wright, PhD
PRINCIPAL INVESTIGATOR
ISTM, Keele University
Frequently Asked Questions
Who can join the NCT06167928 clinical trial?
This trial is open to participants of all sexes, studying Osteoarthritis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06167928 currently recruiting?
Yes, NCT06167928 is actively recruiting participants. Contact the research team at karina.wright1@nhs.net for enrollment information.
Where is the NCT06167928 trial being conducted?
This trial is being conducted at Oswestry, United Kingdom.
Who is sponsoring the NCT06167928 clinical trial?
NCT06167928 is sponsored by Keele University. The principal investigator is Karina T Wright, PhD at ISTM, Keele University. The trial plans to enroll 325 participants.