NCT07827924 Designing a Large Language Model Architecture for Shared Decision Making and Informed Intentions
| NCT ID | NCT07827924 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Harding Center for Risk Literacy |
| Condition | Shared Decision Making |
| Study Type | INTERVENTIONAL |
| Enrollment | 330 participants |
| Start Date | 2026-10-23 |
| Primary Completion | 2026-10-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 330 participants in total. It began in 2026-10-23 with a primary completion date of 2026-10-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study investigates a novel, agentic Large Language Model (LLM) architecture designed to facilitate Shared Decision-Making (SDM) in healthcare. While patients increasingly use standard LLMs for health information, these models often struggle with multi-turn conversations and fail to adapt to varying reading levels, disadvantaging vulnerable groups. By utilizing an agentic state-machine, this project aims to overcome common LLM deficits-such as context loss and uncritical agreement-to ensure clinically accurate, participatory patient conversations. The study evaluates whether this architecture improves informed decision-making compared to standard LLMs, particularly for patients with low health literacy.
Eligibility Criteria
Inclusion Criteria: * Biological sex: Female. * Age: 40 to 70 years old. * Country of residence: United States (US) or United Kingdom (UK). * Language: Native English speaker (English as first language). * Registered and verified user on the academic research platform Prolific. * Able to read, understand, and provide informed consent digitally. Exclusion Criteria: * Individuals who do not meet the automated pre-screening criteria on the Prolific platform. * Inability to use or access a computer, smartphone, or internet browser required to complete the digital study. Note: Quotas will be enforced during recruitment to ensure a 50/50 stratified split between participants with and without university entrance qualifications to guarantee variance in educational backgrounds. Once a quota is filled, further participants matching that educational profile will be excluded. * Addendum: Women with BC symptoms
Contact & Investigator
Felix G Rebitschek, PhD
PRINCIPAL INVESTIGATOR
Harding Center for Risk Literacy
Frequently Asked Questions
Who can join the NCT07827924 clinical trial?
This trial is open to female participants only, aged 40 Years or older, up to 70 Years, studying Shared Decision Making. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07827924 currently recruiting?
Yes, NCT07827924 is actively recruiting participants. Contact the research team at felix.rebitschek@fgw-brandenburg.de for enrollment information.
Where is the NCT07827924 trial being conducted?
This trial is being conducted at Neuruppin, Germany.
Who is sponsoring the NCT07827924 clinical trial?
NCT07827924 is sponsored by Harding Center for Risk Literacy. The principal investigator is Felix G Rebitschek, PhD at Harding Center for Risk Literacy. The trial plans to enroll 330 participants.