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Recruiting NCT05847634

NCT05847634 Depth of Sedation and Its Impact on Cerebrovascular Reactivity in Acute Respiratory Distress Syndrome: a Pilot Analysis

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Clinical Trial Summary
NCT ID NCT05847634
Status Recruiting
Phase
Sponsor University of Manitoba
Condition ARDS, Human
Study Type OBSERVATIONAL
Enrollment 40 participants
Start Date 2024-11-25
Primary Completion 2026-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Masimo O3 NIRS cerebral oximetry and SedLine processed EEG

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 40 participants in total. It began in 2024-11-25 with a primary completion date of 2026-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Investigation of the feasibility of monitoring processed transcutaneous electroencephalography (EEG), a method of interpreting brain activity, and near-infrared spectroscopy (NIRS), a method of determining levels of tissue oxygenation (StO2) in the brain, for patients with acute respiratory distress syndrome (ARDS) in the ICU.

Eligibility Criteria

Inclusion Criteria: * Adult patient admitted to the ICU * ARDS confirmed according to the Berlin Definition * Invasive mechanical ventilation * Deep sedation and/or neuromuscular blockade required for ARDS treatment at the discretion of the treating medical team * Application of monitoring devices feasible Exclusion Criteria: * More than 24 hours elapsed since ICU admission * Death is deemed imminent and inevitable during the next 24 hours * Known allergy to a textile component of the device * Consent declined from patient or authorized third party * The treating clinician believes that participation in the study would not be in the best interest of the patient

Contact & Investigator

Central Contact

Asher Mendelson, MD PhD

✉ asher.mendelson@umanitoba.ca

📞 204-787-8059

Principal Investigator

Asher Mendelson, MD PhD

PRINCIPAL INVESTIGATOR

University of Manitoba

Frequently Asked Questions

Who can join the NCT05847634 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying ARDS, Human. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05847634 currently recruiting?

Yes, NCT05847634 is actively recruiting participants. Contact the research team at asher.mendelson@umanitoba.ca for enrollment information.

Where is the NCT05847634 trial being conducted?

This trial is being conducted at Winnipeg, Canada.

Who is sponsoring the NCT05847634 clinical trial?

NCT05847634 is sponsored by University of Manitoba. The principal investigator is Asher Mendelson, MD PhD at University of Manitoba. The trial plans to enroll 40 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology