NCT05891873 Delirium in the (Neuro)Intensive/Critical Care in the Adult and Paediatric Czech Populations
| NCT ID | NCT05891873 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Masaryk University |
| Condition | Delirium |
| Study Type | OBSERVATIONAL |
| Enrollment | 700 participants |
| Start Date | 2023-09-07 |
| Primary Completion | 2027-05 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 700 participants in total. It began in 2023-09-07 with a primary completion date of 2027-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Intensive and critical care in the intensive care unit (ICU) is often associated with ICU delirium and post-ICU dementia, regardless of the nature of the primary disease or insult. Optimal practical management of ICU delirium including its screening, prevention, and treatment, is an integral part of the current recommendations for optimal ICU care, but there are large gaps in the knowledge about the optimal and most effective prevention and treatment of this complication. Information on the actual implementation of these recommendations in the Czech Republic is lacking. The diagnosis of delirium is particularly challenging in neurointensive care patients (due to overlap with symptoms of primary brain lesions) and in a paediatric population. A complementary multicentre observational 4-year follow-up study, performed in an adult neurointensive/critical care stroke cohort and in a paediatric intensive/critical care cohort in centres following currently recommended preventive measures (Delusion-deep-cz) will investigate the incidence of ICU delirium and post-ICU dementia and their modifiable and non-modifiable predisposing and precipitating risk factors. Objectives are to determine the optimal methods for diagnostic screening of these complications and for the differential diagnosis of conditions mimicking delirium (non-convulsive epileptic state) or symptoms hindering its diagnosis (aphasia), and to study the association between sleep disturbances and ICU delirium to verify the role of sleep in the pathophysiology of delirium.
Eligibility Criteria
Inclusion Criteria: * Neurointensive/neurocritical group (N-ICU): patients with acute ischaemic or haemorrhagic stroke admitted to the Stroke Unit or ICU of the Department of Neurology, University Hospital Brno (NK-UHB). * Paediatric intensive/critical group (P-ICU): children aged 6-18 years, admitted to the Paediatric ICU - Department of Paediatric Anaesthesiology and Intensive Care (KDAR-UHB) with a stay of at least 24 hours (including postoperative care). Exclusion Criteria: * (N-ICU) severe trauma with short life expectancy (days) * duration of the ICU stay shorter than 24 hours
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05891873 clinical trial?
This trial is open to participants of all sexes, studying Delirium. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05891873 currently recruiting?
Yes, NCT05891873 is actively recruiting participants. Contact the research team at bednarik.josef@fnbrno.cz for enrollment information.
Where is the NCT05891873 trial being conducted?
This trial is being conducted at Brno, Czechia.
Who is sponsoring the NCT05891873 clinical trial?
NCT05891873 is sponsored by Masaryk University. The trial plans to enroll 700 participants.