NCT07699666 Delayed Versus Immediate Cord Clamping in Preterm Birth
| NCT ID | NCT07699666 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Faculty of Medicine of Tunis |
| Condition | Preterm Birth Complication |
| Study Type | INTERVENTIONAL |
| Enrollment | 200 participants |
| Start Date | 2025-10-02 |
| Primary Completion | 2026-08-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 200 participants in total. It began in 2025-10-02 with a primary completion date of 2026-08-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this study is to evaluate whether delayed cord clamping improves early neonatal outcomes compared with immediate clamping in preterm birth. Preterm infants are at higher risk of neonatal complications, and the timing of cord clamping may influence placental transfusion and neonatal adaptation after birth. Delayed cord clamping may increase blood volume, improve iron stores, and reduce some neonatal morbidities, while immediate cord clamping is still commonly practiced in many settings. In this study, preterm newborns are assigned to either delayed or immediate cord clamping according to a predefined protocol. Early neonatal outcomes, including respiratory status, need for resuscitation, hemoglobin levels, and early morbidity and mortality, will be assessed. The study is conducted in a tertiary maternity center in Tunisia.
Eligibility Criteria
Inclusion Criteria: * Preterm neonates born at gestational age between 32 and 37 weeks * Live-born infants delivered in the study center * Singleton pregnancies * Parental consent obtained when applicable according to institutional ethical requirements Exclusion Criteria: * Major congenital malformations or chromosomal abnormalities * Need for immediate advanced resuscitation at birth * Severe fetal distress requiring emergency obstetric intervention incompatible with protocol allocation * Placental conditions contraindicating delayed cord clamping (e.g., placental abruption with maternal instability, placenta previa bleeding, Placenta accreta spectrum) * Intra Uterin Growth Restriction with abnormal umbilical artery Doppler velocimetry
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07699666 clinical trial?
This trial is open to participants of all sexes, aged 0 Days or older, studying Preterm Birth Complication. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07699666 currently recruiting?
Yes, NCT07699666 is actively recruiting participants. Contact the research team at mohammedamine.hannachi@fmt.utm.tn for enrollment information.
Where is the NCT07699666 trial being conducted?
This trial is being conducted at Tunis, Tunisia.
Who is sponsoring the NCT07699666 clinical trial?
NCT07699666 is sponsored by Faculty of Medicine of Tunis. The trial plans to enroll 200 participants.