NCT07748962 Decoding the Neural Mechanisms Underlying Postural Instability and Gait Dysfunction in Parkinson's Disease
| NCT ID | NCT07748962 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The Cleveland Clinic |
| Condition | Parkinson Disease |
| Study Type | INTERVENTIONAL |
| Enrollment | 5 participants |
| Start Date | 2026-12-09 |
| Primary Completion | 2027-03-18 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 5 participants in total. It began in 2026-12-09 with a primary completion date of 2027-03-18.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to learn how brain signals are related to freezing of gait (FOG) and balance problems in Parkinson's disease (PD) and to study how different deep brain stimulation (DBS) settings may affect these symptoms.
Eligibility Criteria
Inclusion Criteria: * You have been diagnosed with Parkinson's disease * You already have a deep brain stimulation (DBS) device implanted as part of your medical care - specifically, the Medtronic Percept DBS device * Your DBS settings have been stable for at least 3 months * You experience freezing of gait (sudden inability to move your feet when trying to walk) * You are able to walk on your own for at least 10 minutes without assistance * You are willing to temporarily stop your Parkinson's medications and have your DBS settings adjusted for study testing * You are able to understand the study and provide consent to participate Exclusion Criteria: * You have a neurological condition other than Parkinson's disease (such as stroke or multiple sclerosis) * You have been diagnosed with dementia or have difficulty understanding the study or giving consent * You currently have alcohol or substance abuse problems * You have hearing or vision problems that would make it difficult to use a virtual reality headset * You have any medical or mental health condition that, in the opinion of the study doctor, would make it unsafe or difficult for you to participate
Contact & Investigator
Jay L Alberts, PhD
PRINCIPAL INVESTIGATOR
The Cleveland Clinic
Frequently Asked Questions
Who can join the NCT07748962 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Parkinson Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07748962 currently recruiting?
Yes, NCT07748962 is actively recruiting participants. Contact the research team at dunlapm4@ccf.org for enrollment information.
Where is the NCT07748962 trial being conducted?
This trial is being conducted at Cleveland, United States.
Who is sponsoring the NCT07748962 clinical trial?
NCT07748962 is sponsored by The Cleveland Clinic. The principal investigator is Jay L Alberts, PhD at The Cleveland Clinic. The trial plans to enroll 5 participants.
Related Trials
Related Intelligence Guides
In-depth guides covering this condition's trials, eligibility, and what to expect.