NCT07385651 Deceased Donor Kidney Storage at 10 Celsius Versus Conventional Storage
| NCT ID | NCT07385651 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Vanderbilt University Medical Center |
| Condition | End Stage Chronic Renal Failure |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2024-11-18 |
| Primary Completion | 2027-06-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2024-11-18 with a primary completion date of 2027-06-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to test how storage temperature of deceased donor kidneys affects kidney function after transplant in adult patients receiving a kidney transplant. The main question it aims to answer is: • Do patients that receive a kidney transplant stored at 10 °C have improved post-transplant kidney function? Researchers will compare patients who receive kidneys stored at 10 °C versus kidneys stored at 4°C (on ice, i.e. conventional storage) to see if kidneys stored at 10 °C have improved function. Participants will: * Be made aware of and consent to receive a kidney transplant that had been stored at 10 °C * Have their urine collected 24 hours after surgery to be analyzed for research
Eligibility Criteria
Participant inclusion criteria 1\. All adult single organ kidney transplant candidates on the waiting list at Vanderbilt University Medical Center (VUMC) will be eligible for enrollment. Participant exclusion criteria 1. Kidney transplant candidates less than 18 years old 2. Kidney transplant candidates that decline consent 3. Transplant candidates listed for multi-organ transplant Deceased donor organ inclusion criteria: 1. Donation after brain death or donation after circulatory death kidney donors, whose health care proxy has consented for donation and the possibility of research 2. Deceased donor kidneys that have been allocated to VUMC as a primary match offer prior to organ procurement will be eligible Deceased donor organ exclusion criteria: 1. Donors whose health care proxy has declined consent for the possibility of research 2. Deceased donor kidneys that have been allocated to VUMC as a backup offer 3. Deceased donor kidneys that have been allocated to VUMC as a post procurement offer 4. Deceased donor kidneys that have already been placed on ice
Contact & Investigator
W. Christian Crannell, MD
PRINCIPAL INVESTIGATOR
Vanderbilt University Medical Center
Frequently Asked Questions
Who can join the NCT07385651 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying End Stage Chronic Renal Failure. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07385651 currently recruiting?
Yes, NCT07385651 is actively recruiting participants. Contact the research team at christian.crannell@vumc.org for enrollment information.
Where is the NCT07385651 trial being conducted?
This trial is being conducted at Nashville, United States.
Who is sponsoring the NCT07385651 clinical trial?
NCT07385651 is sponsored by Vanderbilt University Medical Center. The principal investigator is W. Christian Crannell, MD at Vanderbilt University Medical Center. The trial plans to enroll 30 participants.