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Recruiting NCT04364373

D2 vs D3 Lymph Node Dissection for Left Colon Cancer

Trial Parameters

Condition Colon Cancer
Sponsor Russian Society of Colorectal Surgeons
Study Type INTERVENTIONAL
Phase N/A
Enrollment 1,381
Sex ALL
Min Age 18 Years
Max Age 75 Years
Start Date 2020-03-31
Completion 2028-12-31
Interventions
Left colon resectionSigmoid colon resectionDistal sigmoid colon resection or anterior resection

Brief Summary

The efficiency of the D3 lymph node dissection is still controversial for left colon cancer patients. This study will try find difference in 5-year overall survival between D2 and D3 lymph node dissection. Investigation of the functional and short-term outcomes will clarify safety of the D3 lymph node dissection.

Eligibility Criteria

Inclusion Criteria: 1. Agreement of the patient to participate in trial 2. Colon cancer (only adenocarcinoma ) 3. The tumor located between the splenic flexure and rectosigmoid junction 4. cT3-Т4а,b 5. cN0-2 6. cM0 7. Tolerance of chemotherapy 8. ASA 1-3 Exclusion Criteria: 1. сТis - Т2, сТ4b (tail of the pancreas, stomach, small bowel, ureter, urinary bladder) 2. Preoperative complications of the tumor (perforation and full bowel 3. obstruction) 3. Previous radiotherapy or chemotherapy 4. Synchronous or metachronous tumors 5. Women during Pregnancy or breast feeding period

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