NCT04364373 D2 vs D3 Lymph Node Dissection for Left Colon Cancer
| NCT ID | NCT04364373 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Russian Society of Colorectal Surgeons |
| Condition | Colon Cancer |
| Study Type | INTERVENTIONAL |
| Enrollment | 1,381 participants |
| Start Date | 2020-03-31 |
| Primary Completion | 2028-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 1,381 participants in total. It began in 2020-03-31 with a primary completion date of 2028-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The efficiency of the D3 lymph node dissection is still controversial for left colon cancer patients. This study will try find difference in 5-year overall survival between D2 and D3 lymph node dissection. Investigation of the functional and short-term outcomes will clarify safety of the D3 lymph node dissection.
Eligibility Criteria
Inclusion Criteria: 1. Agreement of the patient to participate in trial 2. Colon cancer (only adenocarcinoma ) 3. The tumor located between the splenic flexure and rectosigmoid junction 4. cT3-Т4а,b 5. cN0-2 6. cM0 7. Tolerance of chemotherapy 8. ASA 1-3 Exclusion Criteria: 1. сТis - Т2, сТ4b (tail of the pancreas, stomach, small bowel, ureter, urinary bladder) 2. Preoperative complications of the tumor (perforation and full bowel 3. obstruction) 3. Previous radiotherapy or chemotherapy 4. Synchronous or metachronous tumors 5. Women during Pregnancy or breast feeding period
Contact & Investigator
Peter Tsarkov, Ph.D
STUDY DIRECTOR
I.M. Sechenov First Moscow State Medical University
Frequently Asked Questions
Who can join the NCT04364373 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Colon Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04364373 currently recruiting?
Yes, NCT04364373 is actively recruiting participants. Contact the research team at balaban@kkmx.ru for enrollment information.
Where is the NCT04364373 trial being conducted?
This trial is being conducted at Moscow, Russia.
Who is sponsoring the NCT04364373 clinical trial?
NCT04364373 is sponsored by Russian Society of Colorectal Surgeons. The principal investigator is Peter Tsarkov, Ph.D at I.M. Sechenov First Moscow State Medical University. The trial plans to enroll 1,381 participants.
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