NCT06600269 Cycling-Based Priming Coordination Training for Enhancing Ataxia Recovery and Brain Plasticity
| NCT ID | NCT06600269 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Chang Gung University |
| Condition | Spinocerebellar Ataxias |
| Study Type | INTERVENTIONAL |
| Enrollment | 40 participants |
| Start Date | 2024-10-04 |
| Primary Completion | 2026-08 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 40 participants in total. It began in 2024-10-04 with a primary completion date of 2026-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Effective walking and balance require not only lower limb muscle strength but also coordinated movement. For individuals with Spinocerebellar Ataxia (SCA), rehabilitation strategies targeting coordination are essential to improving mobility and reducing the burden on caregivers. However, evidence-based rehabilitation approaches for ataxia remain limited. Recent studies suggest that improvements in motor learning are often accompanied by changes in cortical excitability. Abnormal cortical excitability in SCA patients may hinder rehabilitation efforts, yet priming strategies-such as exercise or specific stimuli-have been shown to enhance motor learning by modulating cortical excitability. Cycling exercise, in particular, has demonstrated the potential to improve coordination and influence cortical plasticity in individuals with SCA, making it a promising priming strategy for coordination training. This clinical trial aims to: 1. Investigate the priming effect and neural mechanisms of acute cycling exercise on coordination training in patients with SCA. 2. Explore the long-term impact of priming cycling training on cortical plasticity and functional mobility in individuals with SCA. This study seeks to provide insights into optimized rehabilitation interventions that could enhance the quality of life and independence for people with SCA.
Eligibility Criteria
Inclusion Criteria: \- Clinical diagnosis of SCA. Exclusion Criteria: * Musculoskeletal injuries on legs * Osteoporosis. * Any peripheral or central nervous system injury or disease patients.
Frequently Asked Questions
Who can join the NCT06600269 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Spinocerebellar Ataxias. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06600269 currently recruiting?
Yes, NCT06600269 is actively recruiting participants. Visit ClinicalTrials.gov or contact Chang Gung University to inquire about joining.
Where is the NCT06600269 trial being conducted?
This trial is being conducted at Taoyuan, Taiwan.
Who is sponsoring the NCT06600269 clinical trial?
NCT06600269 is sponsored by Chang Gung University. The trial plans to enroll 40 participants.