NCT07371481 CTG Versus Collagen Matrix for Peri-Implant Soft Tissue Augmentation
| NCT ID | NCT07371481 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Hanoi Medical University |
| Condition | Peri-implant Soft Tissue Deficiency |
| Study Type | INTERVENTIONAL |
| Enrollment | 46 participants |
| Start Date | 2026-01-01 |
| Primary Completion | 2027-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 46 participants in total. It began in 2026-01-01 with a primary completion date of 2027-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized controlled trial compares two techniques for peri-implant soft tissue augmentation in the mandibular molar region: an autogenous connective tissue graft (CTG) and a collagen matrix. Adult patients requiring implant treatment with insufficient peri-implant soft tissue thickness will be randomly assigned to receive either CTG or a collagen matrix at the time of implant surgery. The study aims to evaluate and compare changes in peri-implant soft tissue thickness, width of keratinized tissue, and soft tissue contour over a 9-month follow-up period, as well as the occurrence of postoperative complications. The results of this study will help determine whether a collagen matrix can provide clinical outcomes comparable to those of connective tissue grafting for peri-implant soft tissue augmentation.
Eligibility Criteria
Inclusion Criteria: Adults aged 18 to 65 years. Patients requiring dental implant treatment in the mandibular molar region. Presence of insufficient peri-implant soft tissue thickness (\< 2 mm). Adequate general health to undergo minor oral surgery. Ability and willingness to provide written informed consent and comply with study procedures. Exclusion Criteria: Systemic conditions or medications that may impair wound healing. Heavy smoking (more than 10 cigarettes per day). History of allergy or hypersensitivity to collagen-based materials. Previous graft failure or complications at the intended implant site. Loss of three or more adjacent teeth in the study area (excluding third molars).
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07371481 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Peri-implant Soft Tissue Deficiency. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07371481 currently recruiting?
Yes, NCT07371481 is actively recruiting participants. Contact the research team at manhphu@hmu.edu.vn for enrollment information.
Where is the NCT07371481 trial being conducted?
This trial is being conducted at Hanoi, Vietnam.
Who is sponsoring the NCT07371481 clinical trial?
NCT07371481 is sponsored by Hanoi Medical University. The trial plans to enroll 46 participants.