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Recruiting NCT06697808

NCT06697808 Cranial Ultrasound for Point of Care Intracranial Pathology Detection in Pediatrics

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Clinical Trial Summary
NCT ID NCT06697808
Status Recruiting
Phase
Sponsor Wake Forest University Health Sciences
Condition Traumatic Brain Injury
Study Type OBSERVATIONAL
Enrollment 169 participants
Start Date 2024-11-24
Primary Completion 2027-04

Eligibility & Interventions

Sex All sexes
Min Age N/A
Max Age 18 Years
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 169 participants in total. It began in 2024-11-24 with a primary completion date of 2027-04.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

To improve patient selection for head CT, a safe and high sensitivity screening neuroimaging modality is needed. Currently many clinicians must make treatment decisions based solely on the patients clinical exam, which has low sensitivity and specificity and low inter-rater reliability. This study is being done to learn more about B-mode cranial point-of-care ultrasound (cPOCUS). Ultrasound has several advantages. It is a safe, non- invasive, low-cost, fast and portable bedside tool without ionizing radiation exposure.

Eligibility Criteria

Inclusion Criteria: * Patients requiring a head computed tomography (CT) or brain MRI as the standard of care * Seen in the pediatric Emergency Department or Pediatric Intensive Care Unit at Atrium Health Wake Forest Brenner Children's Hospital or Levine Children's Hospital Exclusion Criteria: * Patients with open skull fractures * Previous hemicraniectomy * Existing surgical defect in the skull * Patients being transitioned to comfort care

Contact & Investigator

Central Contact

Denise Fraga, MD

✉ Denise.Fraga@advocatehealth.org

📞 704-355-3181

Principal Investigator

Denise Fraga, MD

PRINCIPAL INVESTIGATOR

Atrium Health Wake Forest Baptist

Frequently Asked Questions

Who can join the NCT06697808 clinical trial?

This trial is open to participants of all sexes, up to 18 Years, studying Traumatic Brain Injury. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06697808 currently recruiting?

Yes, NCT06697808 is actively recruiting participants. Contact the research team at Denise.Fraga@advocatehealth.org for enrollment information.

Where is the NCT06697808 trial being conducted?

This trial is being conducted at Charlotte, United States.

Who is sponsoring the NCT06697808 clinical trial?

NCT06697808 is sponsored by Wake Forest University Health Sciences. The principal investigator is Denise Fraga, MD at Atrium Health Wake Forest Baptist. The trial plans to enroll 169 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology