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Recruiting NCT04558450

NCT04558450 Covid-19 Effects on Arterial Stiffness and Vascular Aging (CARTESIAN)

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Clinical Trial Summary
NCT ID NCT04558450
Status Recruiting
Phase
Sponsor Assistance Publique - Hôpitaux de Paris
Condition Covid19
Study Type INTERVENTIONAL
Enrollment 360 participants
Start Date 2020-09-21
Primary Completion 2023-03

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
carotid-femoral pulse-wave velocity

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 360 participants in total. It began in 2020-09-21 with a primary completion date of 2023-03.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of the study is to evaluate the presence of early vascular aging 6 months and 12 months after COVID-19 infection.

Eligibility Criteria

Inclusion Criteria: * age \>18 years, both sexes; * written informed consent; * affiliation to a social security regime; * a recent diagnosis of COVID19 (6±3 months) proven by PCR or serology (for group 1,2,3) * hospitalization in intensive care unit for COVID19 (for group 1) * hospitalization in a medicine unit for COVID19 (for group 2) * no hospitalization for COVID19 or hospitalization less than 24h (for group 3) * a negative test for SARS-nCOV2 infection (PCR or serology)(for group 4) Exclusion Criteria: * Age \<18 years * Inability to express consent of the study * Diseases carrying out a life -expectancy \<1 year according to clinical judgment * Pregnancy and breastfeeding * Foreseen inability to attend scheduled visits

Contact & Investigator

Central Contact

Rosa Maria BRUNO, MD

✉ rosa-maria.bruno@inserm.fr

📞 +33 1 53 98 79 67

Principal Investigator

Pierre BOUTOUYRIE, MD PHD

PRINCIPAL INVESTIGATOR

Assistance Publique - Hôpitaux de Paris

Frequently Asked Questions

Who can join the NCT04558450 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Covid19. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04558450 currently recruiting?

Yes, NCT04558450 is actively recruiting participants. Contact the research team at rosa-maria.bruno@inserm.fr for enrollment information.

Where is the NCT04558450 trial being conducted?

This trial is being conducted at Nancy, France, Paris, France, Rouen, France.

Who is sponsoring the NCT04558450 clinical trial?

NCT04558450 is sponsored by Assistance Publique - Hôpitaux de Paris. The principal investigator is Pierre BOUTOUYRIE, MD PHD at Assistance Publique - Hôpitaux de Paris. The trial plans to enroll 360 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology