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Recruiting NCT06503640

Coronary Microvascular Dysfunction in Angina Patients With Non-obstructive Coronary Artery Disease (ANOCA-CMD)

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Trial Parameters

Condition Angina Patients With Non-obstructive Coronary Artery Disease
Sponsor China-Japan Friendship Hospital
Study Type OBSERVATIONAL
Phase N/A
Enrollment 100
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2023-07-01
Completion 2024-12-31

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Brief Summary

The goal of this observational study is to explore the incidence and effect on prognosis of coronary microvascular dysfunction in patients present of stable anginal symptoms, a clinical indication for invasive coronary angiography, and no hemodynamically significant epicardial coronary artery disease, defined as fractional flow reserve (FFR) \>0.80.

Eligibility Criteria

Inclusion Criteria: * presence of stable anginal symptoms, a clinical indication for invasive coronary angiography, and no hemodynamically significant epicardial coronary artery disease, defined as fractional flow reserve (FFR) \>0.80 Exclusion Criteria: 1. acute myocardial infarction 2. significant valvular heart disease 3. advanced chronic kidney disease 4. patients with significant epicardial coronary artery stenosis (\>70% in major vessels by diagnostic coronary angiography) needing percutaneous coronary intervention 5. patients unable to provide written informed consent

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