NCT07571473 CoreSys Monitoring for Intraoperative Stress Management in Abdominal Hysterectomy
| NCT ID | NCT07571473 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Hospital Provincial de Rosario |
| Condition | Surgical Stress Response |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2025-01-08 |
| Primary Completion | 2026-05-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2025-01-08 with a primary completion date of 2026-05-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized controlled trial evaluates whether intraoperative guidance using the CoreSys monitor reduces the surgical stress response in patients undergoing elective open abdominal hysterectomy. Surgical stress involves complex hemodynamic, endocrine, and inflammatory responses that may negatively impact postoperative recovery. Patients will be randomized to either anesthesia guided by conventional clinical and hemodynamic parameters or anesthesia additionally guided by CoreSys-derived indices of consciousness, nociception, and stress activity. The primary objective is to assess whether CoreSys-guided anesthesia attenuates stress biomarkers, including interleukin-6 (IL-6), cortisol and glycemia.
Eligibility Criteria
Inclusion Criteria: * Female patients aged 18-70 years * Scheduled elective open abdominal hysterectomy in the morning * Written informed consent Exclusion Criteria: * Refusal to participate * Significant endocrine/metabolic disease * Pacemaker or major arrhythmias * Contraindication to epidural anesthesia
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07571473 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 70 Years, studying Surgical Stress Response. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07571473 currently recruiting?
Yes, NCT07571473 is actively recruiting participants. Contact the research team at marianacianciow@gmail.com for enrollment information.
Where is the NCT07571473 trial being conducted?
This trial is being conducted at Rosario, Argentina.
Who is sponsoring the NCT07571473 clinical trial?
NCT07571473 is sponsored by Hospital Provincial de Rosario. The trial plans to enroll 30 participants.