This study compares two different types of laser eye surgery techniques to correct vision problems like nearsightedness, farsightedness, and astigmatism. Each participant will have one eye treated with wave-front optimized technology and the other eye treated with wave-front guided technology, and neither the patient nor evaluators will know which technique is being used on which eye until the study is complete.
Key Objective: This trial tests whether wave-front guided ablation provides better vision correction outcomes compared to wave-front optimized ablation for PRK or LASIK surgery.
Who to Consider: Adults with refractive errors (nearsightedness, farsightedness, or astigmatism) who are candidates for PRK or LASIK surgery and willing to have both eyes treated with different laser techniques should consider enrolling.
Trial Parameters
Brief Summary
This is a prospective randomized contralateral double-masked study. Each patient will be randomized as to which eye undergoes wave-front optimized (WFO) vs. wave-front guided (WFG) during Photorefractive keratectomy (PRK) or Laser-assisted in situ Keratomileusis (LASIK) surgery to determine which ablation profile provides the best visual outcome.
Eligibility Criteria
Inclusion Criteria: * Meet requirements for PRK or LASIK i.e., Stable \<= .5 D change MRSE) * DOD beneficiaries age 21-50 years * Local pts (w/i 60 mi) who will be in the area for at least 6 months post surgery * Willing to complete all required follow-up visits Exclusion Criteria: * No meeting requirements for PRK or LASIK * Desiring monovision treatment * Anisometropia \>2D spherical equivalent * Prior ocular surgeries / trauma / problem * History of dry eyes * Hyperopia * Mixed astigmatism * Inability to capture VARIO topolyzer scans * Pregnant (or who plans to be within 6 months after surgery) * Breastfeeding any time during the study * History of herpetic disease