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Recruiting Phase 4 NCT06784882

Continuous Versus Single Injection Adductor Canal Blocks for Outpatient Total Knee Arthroplasty

Trial Parameters

Condition Acute Postoperative Pain
Sponsor University of California, San Diego
Study Type INTERVENTIONAL
Phase Phase 4
Enrollment 40
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2025-06-01
Completion 2025-12-01
Interventions
continuous peripheral nerve block with OnQ pumpsingle injection nerve block

Brief Summary

This is a single-center pilot study to determine if an adductor canal continuous nerve block is superior to single injection nerve block following total knee arthroplasty. Investigators will randomize participants to either continuous nerve block or single injection nerve block for the adductor canal preoperatively. They will assess differences in pain (measured in numeric rating scale), opioid consumption, and physical therapy milestones from postoperative day 0 to 7.

Eligibility Criteria

Inclusion Criteria: 1. Adult participants of at least 18 years of age 2. Undergoing a primary, unilateral, total knee arthroplasty 3. Planned single-injection adductor canal nerve block 4. Weight \> 50 kg (to minimize the risk of local anesthetic toxicity) Exclusion Criteria: 1. chronic opioid or tramadol use: daily oxycodone equivalents \> 20 mg for \> 4 weeks 2. neuro-muscular deficit of the surgical limb 3. moderate pain (NRS \> 3) in an anatomic location other than the surgical site 4. planned hospital admission following surgery 5. history of opioid misuse 6. those who lack capacity to complete informed consent 7. inability to contact the investigators during the treatment period, and vice versa (e.g., lack of telephone access) 8. incarceration 9. pregnancy 10. allergy to amide local anesthetics

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