NCT05945043 Continuation Of a Study to Investigate the Effect of Thoracocentesis on Neural Respiratory Drive in Pleural Effusion
| NCT ID | NCT05945043 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Guy's and St Thomas' NHS Foundation Trust |
| Condition | Pleural Effusion |
| Study Type | OBSERVATIONAL |
| Enrollment | 124 participants |
| Start Date | 2023-11-15 |
| Primary Completion | 2027-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 124 participants in total. It began in 2023-11-15 with a primary completion date of 2027-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The aim of this study is to better understand the relationship between pleural effusions and breathlessness in patients with unilateral pleural effusions and breathlessness who require pleural fluid removal for its management.
Eligibility Criteria
Inclusion Criteria: * Age 18 years or above * Has a unilateral pleural effusion AND 1. require thoracocentesis OR 2. chest drain insertion (main study only) OR 3. has an IPC in situ (main study only) Exclusion Criteria: * Inability to consent * Any contraindications to the proposed pleural procedure * Haemodynamic or clinical instability that precludes from the safe completion of required pre-procedural measurements * Inability to identify surface landmarks for surface EMG electrode placement * Past medical history of diaphragmatic paralysis (diaphragm sub study only)
Contact & Investigator
Patrick Murphy, MBBS BSc
PRINCIPAL INVESTIGATOR
Guy's and St Thomas' NHS Foundation Trust
Frequently Asked Questions
Who can join the NCT05945043 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Pleural Effusion. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05945043 currently recruiting?
Yes, NCT05945043 is actively recruiting participants. Contact the research team at junyi.zhang@gstt.nhs.uk for enrollment information.
Where is the NCT05945043 trial being conducted?
This trial is being conducted at London, United Kingdom.
Who is sponsoring the NCT05945043 clinical trial?
NCT05945043 is sponsored by Guy's and St Thomas' NHS Foundation Trust. The principal investigator is Patrick Murphy, MBBS BSc at Guy's and St Thomas' NHS Foundation Trust. The trial plans to enroll 124 participants.