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Recruiting NCT04690972

"Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".

Trial Parameters

Condition Chronic Liver Disease and Cirrhosis
Sponsor Institut National de la Santé Et de la Recherche Médicale, France
Study Type OBSERVATIONAL
Phase N/A
Enrollment 800
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2021-01-14
Completion 2021-01-18
Interventions
Blood sample during surgeryTaking an additional biopsyBlood sample during diagnostic test

Brief Summary

Development of preclinical translational models for chronic liver tumors and diseases study, such as spheroids cultured in autologous medium and murine xenograft models to test the efficacy of new therapeutic strategies.

Eligibility Criteria

Inclusion Criteria: 1. Patients * diagnosed with chronic liver disease (viral or not) * diagnosed with at least one liver nodule for which a biopsy is planned as part of the care * for hepatobiliary surgery planned as part of care * for locoregional treatment for HCC is indicated 2. Patients able to receive and understand information relating to the study and give their written informed consent 3. Patients affiliated to the French social security system Exclusion Criteria: 1. Minor patients 2. Patients under legal protection, 3. Patients subject to legal protection or unable to express their consent, 4. Patients in a situation of social fragility, 5. Pregnant or breastfeeding woman, 6. No signing of informed consent.

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