NCT06875804 Compressive Myofascial Release of the Vastus Lateralis on Lateral Patellar Tracking in Patellofemoral Pain Syndrome
| NCT ID | NCT06875804 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Riphah International University |
| Condition | Patellofemoral Pain Syndrome |
| Study Type | INTERVENTIONAL |
| Enrollment | 24 participants |
| Start Date | 2025-01-02 |
| Primary Completion | 2025-09-02 |
Eligibility & Interventions
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 24 participants in total. It began in 2025-01-02 with a primary completion date of 2025-09-02.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Patellofemoral Pain Syndrome is a prevalent condition characterized by anterior knee pain, often exacerbated by activities such as squatting, running, and stair climbing. This condition is frequently associated with improper patellar tracking, particularly lateral displacement, which can be influenced by various factors including muscular imbalances and tightness. The vastus lateralis muscle, part of the quadriceps group, is often implicated in contributing to lateral patellar tracking due to its attachment and alignment. Compressive myofascial release (CMFR) is a therapeutic technique aimed at reducing muscle tightness and restoring optimal muscle function. This study will explore the effects compressive myofascial release on the vastus lateralis in improving patellar tracking in patients diagnosed with Patellofemoral Pain Syndrome.The methodology of this study involves a randomized controlled trial with a sample of patients diagnosed with Patellofemoral Pain Syndrome. Non-probability convenience sampling technique will be used and participants will be recruited in groups after randomization. Participants(n=26) will be divided into two groups: the intervention group (n=13) receiving compressive myofascial release on the vastus lateralis, and a control group receiving(n=13) a routine treatment. The intervention will be administered over a period of four weeks, with sessions occurring three times weekly. Patellar tracking will be assessed using q-angle analysis both pre- and post-intervention. Additionally, subjective measures of pain and functional ability will be evaluated using the Numeric pain rating scale (NPRS) and the Kujala Patellofemoral Score. Data analysis will focus on comparing the changes in lateral patellar displacement and patient-reported outcomes between the two groups to determine the efficacy of compressive myofascial release in correcting lateral patellar tracking and alleviating symptoms of Patellofemoral Pain Syndrome. SPSS version 25 will be used for data analysis
Eligibility Criteria
Inclusion Criteria: * Age group between 20 to 40 years * Male and female gender * Diagnosed cases of Patellofemoral syndrome * Participants with positive J sign and Clarke's test * Pain provoked during knee loading physical activity, such as jumping, running, squatting, or going up or down stairs in last 3 months * Presence of excessive lateral patellar tracking on axial view radiographs Exclusion Criteria: * History of knee surgery in the past year. * Any contraindications to myofascial release therapy, such as active infections, open wounds. * Presence of hip pathology or other knee conditions such as ligament tears, meniscal injuries, Osgood-Schlatter or Sinding-Larsen-Johanssen syndrome or jumpers knee * Participants with a history of trauma or repetitive episodes of patellar subluxation or dislocation * Use of intra-articular corticosteroid injections * Presence of auto-immune disorder (spondylolisthesis, spondylitis, Rheumatoid arthritis etc.) other than knee OA or systemic conditions such as severe cardiovascular disease
Contact & Investigator
Ghulam Fatima, PHD*
PRINCIPAL INVESTIGATOR
Riphah International University
Frequently Asked Questions
Who can join the NCT06875804 clinical trial?
This trial is open to participants of all sexes, aged 20 Years or older, up to 40 Years, studying Patellofemoral Pain Syndrome. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06875804 currently recruiting?
Yes, NCT06875804 is actively recruiting participants. Contact the research team at imran.amjad@riphah.edu.pk for enrollment information.
Where is the NCT06875804 trial being conducted?
This trial is being conducted at Lahore, Pakistan.
Who is sponsoring the NCT06875804 clinical trial?
NCT06875804 is sponsored by Riphah International University. The principal investigator is Ghulam Fatima, PHD* at Riphah International University. The trial plans to enroll 24 participants.