NCT07103317 Comprehensive Coronary Physiology in Patients With Angina With Nonobstructive Coronary Arteries - Czech Republic
| NCT ID | NCT07103317 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital, Motol |
| Condition | ANOCA |
| Study Type | OBSERVATIONAL |
| Enrollment | 1,000 participants |
| Start Date | 2023-04-20 |
| Primary Completion | 2027-01-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 1,000 participants in total. It began in 2023-04-20 with a primary completion date of 2027-01-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Coronary artery disease (CAD) is a leading cause of morbidity and mortality. While cardiologists have been focused on discrete, visible stenoses of coronary arteries, there is increasing awareness of the importance of microcirculation and vasospastic disorders in causing angina. The microvascular bed is composed of vessels smaller than 400 microns in diameter. Their network is significantly larger than that of the epicardial vessels and serves essential functions, including regulating myocardial blood flow and cellular metabolism. Angina pectoris, a most frequent symptom of CAD or myocardial ischemia, was assumed to be caused by significant stenosis of the epicardial coronary artery. However, it was found that in over 50% of cases, there was no obstructive CAD, which is described as angina with no obstructive coronary arteries (ANOCA) or ischemia with no obstructive coronary arteries (INOCA), according to the clinical setting.
Eligibility Criteria
Inclusion Criteria: * Adults of both sexes older than 18 years * Angina symptoms or angina equivalent * Referred to cath lab for evaluation of CAD * Invasive physiology testing performed (microcirculation testing +/- vasospasm testing) Exclusion Criteria: * Persons under the age of 18 * Pregnant of nursing * No coronary physiology measurements were performed
Contact & Investigator
Petr Kala, M.D., Ph.D.
PRINCIPAL INVESTIGATOR
University Hospital Motol, Charles University
Frequently Asked Questions
Who can join the NCT07103317 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying ANOCA. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07103317 currently recruiting?
Yes, NCT07103317 is actively recruiting participants. Contact the research team at petr.kala@fnmotol.cz for enrollment information.
Where is the NCT07103317 trial being conducted?
This trial is being conducted at Prague, Czechia.
Who is sponsoring the NCT07103317 clinical trial?
NCT07103317 is sponsored by University Hospital, Motol. The principal investigator is Petr Kala, M.D., Ph.D. at University Hospital Motol, Charles University. The trial plans to enroll 1,000 participants.