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Recruiting NCT06243848

NCT06243848 Comparison of Ultrasound-Guided Injection With Median Nerve Decompression Surgery in Carpal Tunnel Syndrome

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Clinical Trial Summary
NCT ID NCT06243848
Status Recruiting
Phase
Sponsor Afyonkarahisar Health Sciences University
Condition Musculoskeletal Diseases
Study Type INTERVENTIONAL
Enrollment 60 participants
Start Date 2024-01-25
Primary Completion 2026-04-24

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 75 Years
Study Type INTERVENTIONAL
Interventions
Minimal Incision Surgery for median nerve decompressionUltrasound-guided perineural injection with 5 cc 5% Dextrose

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 60 participants in total. It began in 2024-01-25 with a primary completion date of 2026-04-24.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The aim of this study is to compare ultrasound-guided perineural injection of the median nerve with classic minimal incision surgical technique for median nerve decompression in patients diagnosed with mild, moderate, and severe carpal tunnel syndrome.

Eligibility Criteria

Inclusion Criteria: * The presence of symptoms such as nocturnal, posture-related, or movement-related paresthesias, along with possible pain, in the area supplied by the median nerve in the hand, lasting for more than 3 months. * Confirmation of mild, moderate or severe CTS through electrophysiological testing. * Numbness and loss of sensation in the hand's regions innervated by the median nerve, as well as weakness in the thenar muscles innervated by the median nerve. * Positive results on either the Phalen test and/or Tinel sign. Exclusion Criteria: * Individuals who may exhibit symptoms mimicking carpal tunnel syndrome, such as cervical radiculopathy, polyneuropathy, brachial plexopathy, or thoracic outlet syndrome. * Patients who have received a previous injection into the carpal tunnel within the past 6 months. * Thenar muscle atrophy. * A history of prior carpal tunnel surgery. * Regular usage of systemic nonsteroidal anti-inflammatory drugs and corticosteroids. * Pregnancy * Patients diagnosed with rheumatoid arthritis, systemic lupus erythematosus, gout, systemic sclerosis, dermatomyositis, or polymyositis. * Malignancy. * Active infections

Contact & Investigator

Central Contact

Ali İzzet AKÇİN, MD

✉ dr.akcin93@gmail.com

📞 +905469347374

Principal Investigator

Nuran EYVAZ, MD

PRINCIPAL INVESTIGATOR

Afyonkarahisar Health Sciences University

Frequently Asked Questions

Who can join the NCT06243848 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Musculoskeletal Diseases. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06243848 currently recruiting?

Yes, NCT06243848 is actively recruiting participants. Contact the research team at dr.akcin93@gmail.com for enrollment information.

Where is the NCT06243848 trial being conducted?

This trial is being conducted at Afyonkarahisar, Turkey (Türkiye).

Who is sponsoring the NCT06243848 clinical trial?

NCT06243848 is sponsored by Afyonkarahisar Health Sciences University. The principal investigator is Nuran EYVAZ, MD at Afyonkarahisar Health Sciences University. The trial plans to enroll 60 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology