NCT07468006 Comparison of Transcutaneous and Blood CO₂ Measurement in Critically Ill Children
| NCT ID | NCT07468006 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Brno University Hospital |
| Condition | Respiratory Insufficiency in Children |
| Study Type | OBSERVATIONAL |
| Enrollment | 20 participants |
| Start Date | 2026-01-01 |
| Primary Completion | 2027-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 20 participants in total. It began in 2026-01-01 with a primary completion date of 2027-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Transcutaneous capnometry (tPCO₂) is a non-invasive method for continuous monitoring of ventilation status. In pediatric intensive care patients, it may reduce the need for repeated arterial or arterialized blood sampling. However, the accuracy of tPCO₂ may be influenced by factors such as peripheral perfusion, skin temperature, and vasopressor therapy. This prospective observational study compares transcutaneous carbon dioxide measurements with arterialized or arterial blood gas PaCO₂ values in children with respiratory insufficiency, including a subgroup receiving vasopressor support.
Eligibility Criteria
Inclusion Criteria: * Age 1-18 years * Diagnosis of respiratory insufficiency or impaired peripheral perfusion * Expected need for more than one arterialized capillary or arterial blood gas sample * Admission to PICU Exclusion Criteria: * Repeated failure of sensor adhesion * Hypothermia \< 35 °C * Time difference \> ±5 minutes between tPCO₂ and blood sampling * Large tPCO₂ variability (\> ±1 kPa) in 15 minutes preceding blood sampling * Non-physiological tPCO₂ values incompatible with life
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07468006 clinical trial?
This trial is open to participants of all sexes, aged 1 Year or older, up to 18 Years, studying Respiratory Insufficiency in Children. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07468006 currently recruiting?
Yes, NCT07468006 is actively recruiting participants. Contact the research team at hana.harazim@gmail.com for enrollment information.
Where is the NCT07468006 trial being conducted?
This trial is being conducted at Brno, Czechia.
Who is sponsoring the NCT07468006 clinical trial?
NCT07468006 is sponsored by Brno University Hospital. The trial plans to enroll 20 participants.