NCT06793527 Comparison of the Efficacy of Celiac Plexus Blockade, ESP and Lidocaine Infusion Under OFA
| NCT ID | NCT06793527 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Jagiellonian University |
| Condition | Regional Anaesthesia |
| Study Type | INTERVENTIONAL |
| Enrollment | 300 participants |
| Start Date | 2025-02-06 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 300 participants in total. It began in 2025-02-06 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Modern anesthesiology, in search of alternatives to opioid-based pain management, is turning to low-opioid and non-opioid protocols. Replacing opioids with non-opioid analgesics, co-analgesics, and regional and local anesthesia techniques allows avoiding the adverse effects of opioids while maintaining satisfactory analgesia. This is of particular importance in bariatric surgery, where reducing the incidence of respiratory depression, sedation, opioid hyperalgesia, and postoperative nausea and vomiting is a priority. Standard non-opioid anesthesia (OFA) includes ketamine, lidocaine, and dexmedetomidine infusions, while regional techniques additionally reduce the need for analgesics. Despite the widespread use of these methods, there is no clear data on the superiority of any of them in bariatric procedures.
Eligibility Criteria
Inclusion Criteria: * Patients over 18 years who underwent laparoscopic bariatric surgery * Must be able to sign agreement for study Exclusion Criteria: * Patients with a history of allergic reactions to drugs * Patients with a history of drug addiction * Patients with chronic pain who require analgesics * History of hospitalization for psychiatric disorders * Preoperative pulse oximetry (SpO2) \< 95 % * bradycardia (HR\<50bpm) * hypotension * atrioventricular block * intraventricular or sinus block * Blood clotting disorders * Pregnant/lactating women * Cognitive impairment * Unable to read consent
Contact & Investigator
Tomasz Skladzien, MD PhD
PRINCIPAL INVESTIGATOR
Jagiellonian University
Frequently Asked Questions
Who can join the NCT06793527 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Regional Anaesthesia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06793527 currently recruiting?
Yes, NCT06793527 is actively recruiting participants. Contact the research team at tomasz.skladzien@uj.edu.pl for enrollment information.
Where is the NCT06793527 trial being conducted?
This trial is being conducted at Krakow, Poland.
Who is sponsoring the NCT06793527 clinical trial?
NCT06793527 is sponsored by Jagiellonian University. The principal investigator is Tomasz Skladzien, MD PhD at Jagiellonian University. The trial plans to enroll 300 participants.