NCT06409923 Comparison of Skeletal Effects of Herbst and Invisalign MA in Growing Patients With KLass II Malocclusion
| NCT ID | NCT06409923 |
| Status | Recruiting |
| Phase | Phase 1 |
| Sponsor | Université Libre de Bruxelles |
| Condition | Mandibular Growth Stimulation |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2024-02-14 |
| Primary Completion | 2027-09-10 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
Phase 1 is the earliest stage of human testing — safety and dosage are the primary focus. Visits are frequent and medical supervision is intensive. You will be among the first people to receive this treatment.
This trial targets 30 participants in total. It began in 2024-02-14 with a primary completion date of 2027-09-10.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to determine and compare the precise skeletal dental and soft tissue effect of Mandibular advancement aligners and Herbst Appliance.
Eligibility Criteria
Inclusion Criteria * ANB greater than 4°. * Angle Class II molar and canine relationship * cervical vertebral maturation (CVM) CVM2/CVM3 Exclusion Criteria: * CVM\> 4 * periodontal disease
Frequently Asked Questions
Who can join the NCT06409923 clinical trial?
This trial is open to participants of all sexes, up to 15 Years, studying Mandibular Growth Stimulation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
What phase is the NCT06409923 trial and what does that mean for participants?
Phase 1 trials are the first stage of human testing. The primary goal is to assess safety and determine appropriate dosage levels. Participants are closely monitored. These trials typically involve a small number of volunteers.
Is NCT06409923 currently recruiting?
Yes, NCT06409923 is actively recruiting participants. Visit ClinicalTrials.gov or contact Université Libre de Bruxelles to inquire about joining.
Where is the NCT06409923 trial being conducted?
This trial is being conducted at Anderlecht, Belgium, Brussels, Belgium.
Who is sponsoring the NCT06409923 clinical trial?
NCT06409923 is sponsored by Université Libre de Bruxelles. The trial plans to enroll 30 participants.