NCT07439614 Comparison of Root Canal Desinfection Protocols
| NCT ID | NCT07439614 |
| Status | Recruiting |
| Phase | — |
| Sponsor | State University of New York at Buffalo |
| Condition | Periapical Periodontitis |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2026-04-01 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 50 participants in total. It began in 2026-04-01 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Evaluate and compare the disinfecting efficacy of two supplementary antimicrobial protocols in teeth with apical periodontitis
Eligibility Criteria
Inclusion Criteria: * Adult patients able to give informed consent and willing/able to comply with study procedures and follow-up. * Molar teeth indicated for endodontic treatment. * Teeth with intact pulp-chamber walls (no extensive coronal destruction). * Necrotic pulp confirmed by pulp testing. * Clinical and radiographic evidence of asymptomatic apical periodontitis. Exclusion Criteria: * Immature teeth * Teeth with calcified or obliterated canals * Teeth with extensive coronal destruction * Teeth with previous endodontic treatment * Symptomatic apical periodontitis * Teeth with periodontal pockets greater than 4 mm * Patients who have received systemic antibiotics in the last 3 months * Patients with a history of diabetes or immune impairment * Pregnant patients
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07439614 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Periapical Periodontitis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07439614 currently recruiting?
Yes, NCT07439614 is actively recruiting participants. Contact the research team at smlyon@buffalo.edu for enrollment information.
Where is the NCT07439614 trial being conducted?
This trial is being conducted at Buffalo, United States.
Who is sponsoring the NCT07439614 clinical trial?
NCT07439614 is sponsored by State University of New York at Buffalo. The trial plans to enroll 50 participants.