Comparison of Pulsed and Thermal Radiofrequency for Trigeminal Neuralgia
Trial Parameters
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Brief Summary
The goal of this clinical trial is to compare the effectiveness of Pulsed Radiofrequency (PRF) with Pulsed and Thermal Radiofrequency (PRF + TRF) in treating Trigeminal Neuralgia (TN) in adults. The main questions it aims to answer are: * Does PRF or PRF + TRF provide better pain relief for patients with trigeminal neuralgia? * What is the safety profile and complication rate of PRF versus PRF + TRF? Researchers will compare the effects of PRF and PRF + TRF to see if thermal lesioning in addition to pulsed RF provides superior long-term pain relief and reduces the need for analgesic medication. Participants will: * Undergo either PRF or PRF + TRF treatment targeting the trigeminal nerve. * Be assessed for pain relief, functional status, and adverse events over a 3-month follow-up period.
Eligibility Criteria
Inclusion Criteria: * Adults aged 18-60 years. * Diagnosis of classical trigeminal neuralgia, as per the International Classification of Headache Disorders criteria * Patients experiencing unilateral, episodic facial pain for at least six months with a Numeric Rating Scale (NRS) score greater than 6, despite medical treatment. * Able to provide informed consent. * Agree to follow the study procedures and attend follow-up visits. Exclusion Criteria: * Patients with secondary trigeminal neuralgia (e.g., due to tumors, multiple sclerosis). * Previous surgery or radiofrequency treatment for trigeminal neuralgia. * Pregnant or breastfeeding women. * Known allergies to anesthetics or other agents used in the procedure. * Significant psychiatric disorders that may interfere with pain assessment or study participation. * Coagulopathy or use of anticoagulants that contraindicate the procedure.