NCT06768424 Comparison of MIST With PRF and GBT With PRF in the Treatment of Intrabony Periodontal Defect. A Prospective RCT
| NCT ID | NCT06768424 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Semmelweis University |
| Condition | Intrabony Periodontal Defect |
| Study Type | INTERVENTIONAL |
| Enrollment | 36 participants |
| Start Date | 2023-12-20 |
| Primary Completion | 2027-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 36 participants in total. It began in 2023-12-20 with a primary completion date of 2027-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The aim is to evaluate in a prospective, randomized, controlled clinical study the healing of a MIST procedure combined with PRF, or GBT combined with PRF. Clinical, radiological evaluation of the regenerative surgical method and the GBT non-surgical therapy in solitaire deep intrabony periodontal defect.
Eligibility Criteria
Inclusion Criteria: * solitaire intrabony periodontal defect at least 4 mm Exclusion Criteria: * Periodontitis with intrabony defect (Intrabony component ≥ 4mm, defect radiological angulation \> 25°, * The patient is able to comply with the study -related procedures (i.e. good level of oral hygiene, follow-up procedures). * Patients must not be heavy smokers (\<5 cigarettes/day). * furcation involvement * Full mouth plaque and bleeding scores (FMPS and FMBS) of \<15% (O'Leary et al. 1972). * The patient is able to fully understand the nature of the study, signed informed consent.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06768424 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Intrabony Periodontal Defect. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06768424 currently recruiting?
Yes, NCT06768424 is actively recruiting participants. Contact the research team at kardpali@gmail.com for enrollment information.
Where is the NCT06768424 trial being conducted?
This trial is being conducted at Budapest, Hungary.
Who is sponsoring the NCT06768424 clinical trial?
NCT06768424 is sponsored by Semmelweis University. The trial plans to enroll 36 participants.