NCT07144267 Comparison of Milrinone and Epinephrine on TAPSE
| NCT ID | NCT07144267 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mansoura University |
| Condition | Cardiac Anaesthesia |
| Study Type | INTERVENTIONAL |
| Enrollment | 102 participants |
| Start Date | 2026-03-01 |
| Primary Completion | 2028-12-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 102 participants in total. It began in 2026-03-01 with a primary completion date of 2028-12-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Cardiopulmonary bypass (CPB) is a critical technology in cardiac surgery, allowing for the temporary replacement of the heart and lung functions during intricate surgical procedures. it has significant post-surgical complications, the most important complications of CPB is right ventricle (RV) dysfunction. Diagnosis and management of RV dysfunction is crucial for maintenance of hemodynamic stability and organ function in early post-operation period and prognostic for later phase.
Eligibility Criteria
Inclusion Criteria: * American Society of Anesthesiologists (ASA) physical status II \& III * Age between 18 and 70 years * Both Gender * Body mass index less than 40 kg/m2 * Ejection fraction of \>40% * Tricuspid annular plane systolic excursion (TAPSE) \< 1.7cm Exclusion Criteria: * Patient refusal. * Preoperative RV impairment * Pulmonary hypertension (estimated pulmonary artery systolic pressure \> 50 mmHg) * Patients with any contraindications to Transesophageal echocardiography (TEE) * Redo or Re-exploration surgery * Patients with chronic kidney disease (serum creatinine \> 1.5 mg/ dl) * Patients with chronic liver disease (child pugh B and C)
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07144267 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Cardiac Anaesthesia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07144267 currently recruiting?
Yes, NCT07144267 is actively recruiting participants. Contact the research team at mahazed@yahoo.com for enrollment information.
Where is the NCT07144267 trial being conducted?
This trial is being conducted at Al Mansurah, Egypt.
Who is sponsoring the NCT07144267 clinical trial?
NCT07144267 is sponsored by Mansoura University. The trial plans to enroll 102 participants.