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Recruiting NCT06202105

Comparison of Laparoscopic and Open Total Gastrectomy for Locally Advanced Gastric Cancer

Trial Parameters

Condition Gastric Cancer
Sponsor University Medical Center Ho Chi Minh City (UMC)
Study Type INTERVENTIONAL
Phase N/A
Enrollment 210
Sex ALL
Min Age 18 Years
Max Age 80 Years
Start Date 2024-08-02
Completion 2032-08-02
Interventions
Laparoscopic gastrectomy

Brief Summary

Evidence of implementation of laparoscopic total gastrectomy (LTG) for locally advanced gastric cancer (GC) remains inadequate. This study aimed to compare short- and mid-term outcomes of LTG versus open total gastrectomy (OTG) for cT2-4a GC.

Eligibility Criteria

Inclusion Criteria: * Pathologic finding by gastric endoscopy: confirmed gastric adenocarcinoma * Age: 18 - 80 year old * Tumor required total gastrectomy for radical treatment * Preoperative cancer stage (CT scan stage): cT2-4aNanyM0 * ASA score: ≤ 3 * Informed consent patients (explanation about our clinical trials is provided to the patients or patrons, if patient is not available) Exclusion Criteria: * Concurrent cancer or patient who was treated due to other cancer before the patient was diagnosed gastric cancer * Bulky lymph node andd/or Para-aortic lymph node metastasis * Combined esophagectomy due to invading to the esophagus * Pregnant patient

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