NCT07036445 Comparison of Interlaminar CT Guided Epidural Platelet Rich Plasma Versus Steroid Injection in Patients With Lumbar Radicular Pain
| NCT ID | NCT07036445 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Clinique du Sport, Bordeaux Mérignac |
| Condition | Herniated Disc |
| Study Type | INTERVENTIONAL |
| Enrollment | 200 participants |
| Start Date | 2025-09-11 |
| Primary Completion | 2028-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 200 participants in total. It began in 2025-09-11 with a primary completion date of 2028-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The treatment of persistent lumbar radicular pain (LRP) using CT-guided epidural steroid injection (ESI) is widely used and associated with rare but serious complications. Platelet-rich plasma (PRP), which has recently been shown to promote healing and the anti-inflammatory process by delivering growth factors and cytokines, could be an alternative and potentially safer option. A previous study showed that PRP was as effective as ESI in treating this condition, without major complications. This study aims to compare these two treatments over the long term (2 years).
Eligibility Criteria
Inclusion Criteria: * Diagnosis of unilateral resistant LRP associated with a herniated disc on MRI images. (Diagnosis of resistance after 6 weeks of appropriate medical treatment). Exclusion Criteria: * Patients with infections, * Patients who have had previous percutaneous corticosteroid injections, * Patients undergoing systemic corticosteroid treatment, * Patients with immune deficiencies, * Patients who are allergic to the contrast medium used, * Pregnant or breastfeeding patients, * Patients with a history of allergies to anesthetics or corticosteroids, * Anticoagulant treatment or blood disorders, patients on antiplatelet therapy * Taking NSAIDs within two weeks prior to the procedure
Frequently Asked Questions
Who can join the NCT07036445 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Herniated Disc. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07036445 currently recruiting?
Yes, NCT07036445 is actively recruiting participants. Visit ClinicalTrials.gov or contact Clinique du Sport, Bordeaux Mérignac to inquire about joining.
Where is the NCT07036445 trial being conducted?
This trial is being conducted at Mérignac, France.
Who is sponsoring the NCT07036445 clinical trial?
NCT07036445 is sponsored by Clinique du Sport, Bordeaux Mérignac. The trial plans to enroll 200 participants.