NCT07496723 Comparison of Diagnostic Methods in Patients Operated for Suspected Appendicitis
| NCT ID | NCT07496723 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Sanliurfa Education and Research Hospital |
| Condition | Acute Appendicitis |
| Study Type | OBSERVATIONAL |
| Enrollment | 200 participants |
| Start Date | 2026-03-18 |
| Primary Completion | 2027-01-31 |
Trial Parameters
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Brief Summary
Acute appendicitis is one of the most common surgical emergencies, but diagnostic uncertainty may still lead to unnecessary appendectomy in some patients. This prospective observational study aims to evaluate the diagnostic performance of computed tomography (CT) reporting and the Appendicitis Inflammatory Response (AIR) score in adult patients undergoing appendectomy for suspected acute appendicitis. The primary objective is to determine the negative appendectomy rate based on final histopathology. Secondary objectives are to assess the agreement between AIR score, CT findings, intraoperative severity grading, and pathology results, and to explore diagnostic performance across patient subgroups. No study-specific intervention beyond routine clinical care will be performed.
Eligibility Criteria
Inclusion Criteria: * Age 18 years or older * Presentation to the emergency department with suspected acute appendicitis * Underwent computed tomography after clinical evaluation * Computed tomography report compatible with acute appendicitis * Underwent appendectomy for presumed acute appendicitis * Provided informed consent Exclusion Criteria: * Age younger than 18 years * Pregnancy * Planned additional surgical intervention in the same session for a reason other than appendicitis * Intraoperative finding of a non-appendiceal pathology requiring a different surgical procedure * Refusal to participate in the study