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Recruiting Phase 4 NCT06569537

Comparison of Compounded Topical Anesthetics

Trial Parameters

Condition Procedural Pain
Sponsor Dartmouth-Hitchcock Medical Center
Study Type INTERVENTIONAL
Phase Phase 4
Enrollment 64
Sex ALL
Min Age 18 Years
Max Age 75 Years
Start Date 2024-10-22
Completion 2026-01
Interventions
Lidocaine topicalBLT

Brief Summary

The primary objective for this pilot study is to evaluate the efficacy of the compounded topical anesthetic Benzocaine 20%/ Lidocaine 8%/Tetracaine 4% (BLT) compared to 4% Lidocaine topical in providing relief of pain during IPL, PDL, and microneedling procedures.

Eligibility Criteria

Inclusion Criteria: * Men and women over 18, but not more than 75 years of age. * Patients who have a regularly scheduled dermatology appointment for Intense Pulse Light (IPL), Pulse Dye Laser (PDL), or microneedling. Exclusion Criteria: * Any subject who has a previous history of allergy, sensitivity, and contraindication to benzocaine, lidocaine, or tetracaine. * Patients with cardiac/respiratory disease, seizure disorder, or neuropathies. * Patients who are under treatment for a dermatologic condition that may interfere with the evaluation of the study. * Pregnant women and women who are breastfeeding. * Patients who report concurrent use of anxiolytics or opiates, which may interfere with the interpretation of results.

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