NCT07894016 Comparison of Amoxicillin, Clindamycin and Azithromycin Single Doses Antibiotic Prophylaxis in Patient Undergoing Lower Third Molar Extraction
| NCT ID | NCT07894016 |
| Status | Recruiting |
| Phase | Phase 4 |
| Sponsor | Dow University of Health Sciences |
| Condition | Wisdom Tooth Removal |
| Study Type | INTERVENTIONAL |
| Enrollment | 105 participants |
| Start Date | 2026-10-20 |
| Primary Completion | 2026-12-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
Phase 4 studies follow an already-approved treatment in real-world conditions to monitor long-term safety and effectiveness.
This trial targets 105 participants in total. It began in 2026-10-20 with a primary completion date of 2026-12-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to learn which drug amongst Amoxicillin, Clindamycin and Azithromycin single dose works better in reducing post-surgical complications in Participants getting lower wisdom teeth pulled. The main question it aims to answer is: • Which single dose drug lowers the post-surgical complications in participants of this study? Researcher will compare three single dose drugs (the administration of the complete amount of an antibiotic medication in one single administration to cure or prevent an infection). Participants will: * Take provided drug one hour before the treatment * Visit the OPD for Reading measurements same day before the surgery, same day after the surgery and third day after the surgery.
Eligibility Criteria
Inclusion Criteria: * Individuals with no history antibiotics for past 1 month * No active infection going * No allergies to any antibiotics, analgesics, local anesthetic * Cases of low to medium difficulty * Age bracket from 18 years or older Exclusion Criteria: * Pregnant women * Lactating mothers * People who have any soft tissue healing disorder * Patient undergone radiotherapy * Patient having kidney or liver disease
Contact & Investigator
Meer M Fawad, Masters of Science
PRINCIPAL INVESTIGATOR
Down University of Health Sciences
Frequently Asked Questions
Who can join the NCT07894016 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Wisdom Tooth Removal. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
What phase is the NCT07894016 trial and what does that mean for participants?
Phase 4 studies are conducted after a treatment has been approved. They monitor long-term safety and real-world effectiveness in a broader patient population.
Is NCT07894016 currently recruiting?
Yes, NCT07894016 is actively recruiting participants. Contact the research team at fawadshaikh55@gmail.com for enrollment information.
Where is the NCT07894016 trial being conducted?
This trial is being conducted at Karachi, Pakistan.
Who is sponsoring the NCT07894016 clinical trial?
NCT07894016 is sponsored by Dow University of Health Sciences. The principal investigator is Meer M Fawad, Masters of Science at Down University of Health Sciences. The trial plans to enroll 105 participants.