NCT06759116 Comparison Between Fentanyl and Dexmedetomidine As Adjuvant to Bupivacaine in Combined IPACK and Adductor Canal Block for Postoperative Analgesia After Knee Surgeries
| NCT ID | NCT06759116 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Zagazig University |
| Condition | Analgesia, Postoperative |
| Study Type | INTERVENTIONAL |
| Enrollment | 111 participants |
| Start Date | 2025-01-10 |
| Primary Completion | 2025-07-10 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 111 participants in total. It began in 2025-01-10 with a primary completion date of 2025-07-10.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study will be undertaken to compare the analgesic effects of of fentanyl versus dexmedetomidine as adjuvant to bupivacaine in combined IPACK and ACB for pain management after total knee arthroplasty.
Eligibility Criteria
Inclusion Criteria: 1 - Patient acceptance 2. Cooperative patients 3. Age: ≥21 and 85\< years' old 4. Sex: both sexes (males or females). 5. Physical status: ASA Ι \& II\& Ш. 6. Body Mass Index (BMI): ≤ 35 kg/m2. 7. Type of operation: elective unilateral knee surgeries (TKA, ACL, knee arthroscopy) Exclusion Criteria: . Patient with any contraindications of regional blocks (as coagulopathy or local infection at injection site) 2. Patients with known history of allergy to the study drugs (bupivacaine, dexmedetomidine and fentanyl). 3\. Advanced hepatic, renal, cardiovascular, neurologic and respiratory diseases. 4.Chronic opioid use (more than 3 months or daily oral morphine \> 5 mg /day for 1 month) \-
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06759116 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, up to 85 Years, studying Analgesia, Postoperative. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06759116 currently recruiting?
Yes, NCT06759116 is actively recruiting participants. Contact the research team at sherifelagamy@yahoo.com for enrollment information.
Where is the NCT06759116 trial being conducted?
This trial is being conducted at El Sharkia, Egypt.
Who is sponsoring the NCT06759116 clinical trial?
NCT06759116 is sponsored by Zagazig University. The trial plans to enroll 111 participants.