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Recruiting NCT06220526

NCT06220526 Comparing Menghini-type Needle and Franseen-type Needle in EBUS-TBNA for Sarcoidosis

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Clinical Trial Summary
NCT ID NCT06220526
Status Recruiting
Phase
Sponsor University Health Network, Toronto
Condition Suspected Sarcoidosis
Study Type INTERVENTIONAL
Enrollment 128 participants
Start Date 2023-08-18
Primary Completion 2026-02-28

Trial Parameters

Condition Suspected Sarcoidosis
Sponsor University Health Network, Toronto
Study Type INTERVENTIONAL
Phase N/A
Enrollment 128
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2023-08-18
Completion 2026-02-28
Interventions
endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)

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Brief Summary

This randomized pilot clinical trial aims to examine whether sample collection with Franseen-type needles are effective for the diagnosis of sarcoidosis, as defined by improved sample quality for pathological diagnosis compared to the conventional Menghini-type needle.

Eligibility Criteria

Inclusion Criteria: * -Any adult patient aged 18 years or older with enlarged mediastinal and/or hilar lymph nodes * (≥10 mm short-axis diameter on a CT scan), suspected as having sarcoidosis based on clinical * history, physical exam, and other investigations, and booked for EBUS-TBNA. Exclusion Criteria: * -Patients that are unable to provide informed consent \- Patients with lymphadenopathy strongly suspected to be secondary to other diseases based on * clinical history, physical exam, and/or other investigations (e.g., lung cancer, lymphoma, * infection).

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