NCT07474493 Comparing Cleaning Tools for Full-Arch Implant-Supported Fixed Prostheses
| NCT ID | NCT07474493 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University |
| Condition | Edentulism |
| Study Type | INTERVENTIONAL |
| Enrollment | 18 participants |
| Start Date | 2026-01-14 |
| Primary Completion | 2027-01-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 18 participants in total. It began in 2026-01-14 with a primary completion date of 2027-01-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
For patients with complete edentulism, full-arch implant-supported fixed prostheses can effectively restore functions such as mastication, esthetics, and speech. Their long-term clinical outcomes are predictable, and patient satisfaction is generally high. However, the probability of biological complications associated with full-arch implant-supported fixed prostheses within 10 years can be as high as 91.2%. Poor oral hygiene and plaque accumulation are important risk factors for these biological complications. Proper cleaning and maintenance are crucial for the long-term success of full-arch implant-supported fixed prostheses. However, the most effective cleaning method remains unclear. Superfloss, interdental brushes, and water floss are commonly used auxiliary cleaning tools, but in vivo studies evaluating their cleaning efficacy are limited. Therefore, a randomized controlled study with a relatively long observation period is needed to better evaluate the cleaning effectiveness of different methods-superfloss, interdental brushes, and water floss-in patients with full-arch implant-supported fixed prostheses. This study adopts a self-controlled, three-phase crossover design. Participants will sequentially use superfloss (S), interdental brushes (I), and a water flosser (W) to clean the surface of full-arch implant-supported fixed prostheses. Each cleaning method will be used for three months, after which a follow-up examination will be conducted. The participants will then switch to the second cleaning method, followed by another evaluation after three months. Finally, they will switch to the third cleaning method, and a final examination will be performed after an additional three months, completing the study.
Eligibility Criteria
Inclusion Criteria: 1. Age ≥18 years; 2. Patients with single-arch or full-arch edentulism / terminal dentition who have completed implant placement and immediate restoration and are scheduled to receive the definitive prosthesis; 3. Patients with good compliance who provide informed consent. Exclusion Criteria: 1. Smoking (≥10 cigarettes per day); 2. Lack of self-care ability and unable to perform prosthesis cleaning independently; 3. Uncontrolled periodontitis in remaining teeth or unstable periodontal condition; 4. Presence of failed implants in the full-arch implant restoration and requiring second implantation.
Frequently Asked Questions
Who can join the NCT07474493 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Edentulism. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07474493 currently recruiting?
Yes, NCT07474493 is actively recruiting participants. Visit ClinicalTrials.gov or contact Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University to inquire about joining.
Where is the NCT07474493 trial being conducted?
This trial is being conducted at Shanghai, China.
Who is sponsoring the NCT07474493 clinical trial?
NCT07474493 is sponsored by Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University. The trial plans to enroll 18 participants.