NCT07740382 Comparative Effects of ESP Block and EOIP Block on Postoperative Respiratory Recovery Following Liver Resection
| NCT ID | NCT07740382 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Menoufia University |
| Condition | Liver Resection |
| Study Type | INTERVENTIONAL |
| Enrollment | 116 participants |
| Start Date | 2026-08-15 |
| Primary Completion | 2027-01-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 116 participants in total. It began in 2026-08-15 with a primary completion date of 2027-01-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study evaluates respiratory recovery as a multidimensional construct using clinically relevant and measurable parameters, including LUS, diaphragmatic excursion, oxygen requirement, and PPCs. The investigators hypothesize that bilateral ESP block improves postoperative respiratory function compared with EOIP block following open hepatic surgery. The investigators further hypothesize that this improvement is mediated, in part, by superior analgesia.
Eligibility Criteria
Inclusion Criteria: * Adult patients aged 18-75 years * Adult with American Society of Anesthesiologists (ASA) physical status I-III * Scheduled for elective hepatic surgery via upper abdominal incisions will be eligible. * All participants will be required to understand the Numeric Rating Scale (NRS) and provide informed consent. Exclusion Criteria: * Patient refusal * Coagulopathy (INR\>1.4 or platelet count\<8 x 104) * Contraindications to fascial plane blocks * Infection at the puncture site * Known allergy to study medications * Chronic opioid use or chronic pain syndromes * Severe chronic respiratory failure requiring home oxygen or noninvasive ventilation * Pregnancy * Body mass index\>40 kg/m² * When ultrasound imaging will be deemed unreliable * Emergency surgery * Hemodynamic instability * Reoperation during the same hospital admission. * Patients scheduled preoperatively for elective postoperative mechanical ventilation or planned ICU intubation.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07740382 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Liver Resection. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07740382 currently recruiting?
Yes, NCT07740382 is actively recruiting participants. Contact the research team at nevinemostafa@gmail.com for enrollment information.
Where is the NCT07740382 trial being conducted?
This trial is being conducted at Alexandria, Egypt.
Who is sponsoring the NCT07740382 clinical trial?
NCT07740382 is sponsored by Menoufia University. The trial plans to enroll 116 participants.