NCT07585305 Comparative Effects of Blood Flow Restriction Resistance Training Versus Blood Flow Restriction Cycling on Pain, Quadriceps Strength, and Functional Outcomes in Athletes With Patellofemoral Pain
| NCT ID | NCT07585305 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Ibadat International University, Islamabad |
| Condition | Patello Femoral Pain Syndrome |
| Study Type | INTERVENTIONAL |
| Enrollment | 48 participants |
| Start Date | 2026-05-10 |
| Primary Completion | 2026-07-10 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 48 participants in total. It began in 2026-05-10 with a primary completion date of 2026-07-10.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized controlled trial compares blood flow restriction (BFR) resistance training (leg press and seated knee extension at 30% 1RM) versus BFR cycling (stationary cycling at low resistance) in 60 athletes (aged 18-40 years) diagnosed with patellofemoral pain syndrome. Both interventions are delivered over 8 weeks (3 sessions/week) with a pneumatic cuff set at 80% limb occlusion pressure. Primary outcomes include pain intensity (NPRS), quadriceps strength (handheld dynamometer), and functional ability (Kujala Anterior Knee Pain Scale), assessed at baseline and post-intervention.
Eligibility Criteria
Inclusion Criteria: 1. Male and female athletes aged 18-40 years 2. Clinically diagnosed with patellofemoral pain syndrome 3. Anterior or retropatellar knee pain of at least 3 months duration 4. Pain provoked by at least two functional activities (e.g., squatting, stair climbing, running, prolonged sitting) 5. Willingness to participate and provide written informed consent Exclusion Criteria: 1. History of knee surgery or significant knee trauma in the past 6 months 2. Presence of ligament, meniscal, or cartilage injuries 3. Neurological, vascular, or systemic inflammatory conditions 4. Contraindications to BFR training (e.g., deep vein thrombosis, uncontrolled hypertension) 5. Pregnancy
Contact & Investigator
Hafsah Gul Khattak, DPT, MS-NMPT
PRINCIPAL INVESTIGATOR
IBADAT INTERNATIONAL UNIVERSITY, ISLAMABAD (IIUI)
Frequently Asked Questions
Who can join the NCT07585305 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 40 Years, studying Patello Femoral Pain Syndrome. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07585305 currently recruiting?
Yes, NCT07585305 is actively recruiting participants. Contact the research team at haroonkhan2k00@gmail.com for enrollment information.
Where is the NCT07585305 trial being conducted?
This trial is being conducted at Islamabad, Pakistan.
Who is sponsoring the NCT07585305 clinical trial?
NCT07585305 is sponsored by Ibadat International University, Islamabad. The principal investigator is Hafsah Gul Khattak, DPT, MS-NMPT at IBADAT INTERNATIONAL UNIVERSITY, ISLAMABAD (IIUI). The trial plans to enroll 48 participants.