NCT05174286 Community Health Workers United to Reduce Colorectal Cancer and Cardiovascular Disease Among People at Higher Risk
| NCT ID | NCT05174286 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Columbia University |
| Condition | Colorectal Cancer |
| Study Type | INTERVENTIONAL |
| Enrollment | 880 participants |
| Start Date | 2023-03-19 |
| Primary Completion | 2026-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 880 participants in total. It began in 2023-03-19 with a primary completion date of 2026-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The overall goal of this study is to develop a comprehensive, culturally tailored community-based colorectal cancer (CRC) prevention model with a dual emphasis on reducing CRC risk along with its CVD risk factors. The study intervention has two components: Screening, Brief Intervention, and Referral to Treatment (SBIRT) to address CRC screening and a web-based lifestyle program called "Alive!" to address CVD risk factors linked to CRC. The C.H.U.R.C.H. Trial (Community Health workers (CHW) United to Reduce Colorectal cancer and cardiovascular disease among people at Higher risk) has four specific aims: (1) to compare the effect of a CHW-Led SBIRT (Intervention) to Referral As Usual (RAU) (Usual Care) on guideline-concordant CRC screening uptake; (2) to evaluate the effect of a Culturally Adapted CHW-linked Alive! (CACA) program incorporated into the intervention arm on dietary inflammatory score (DIS); (3) to evaluate the effect of CACA on changes in Life Simple-7 (LS7) scores; and (4) to examine the multi-level contextual mechanisms and factors influencing CHW effectiveness, reach, and implementation of CRC screening uptake and CACA activities through a mixed-methods process evaluation. Given the broad reach and influence of churches, results from this study can be used to inform future scale up of this multi-pronged intervention.
Eligibility Criteria
Inclusion Criteria: 1. English-speaking 2. Aged 45 years and older 3. Not up-to-date with CRC 4. Working telephone 5. Can provide informed consent Exclusion Criteria: 1. Non-English speaking 2. \<45 years old
Contact & Investigator
Olajide A. Williams, MD, MS
PRINCIPAL INVESTIGATOR
Columbia University
Frequently Asked Questions
Who can join the NCT05174286 clinical trial?
This trial is open to participants of all sexes, aged 45 Years or older, studying Colorectal Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05174286 currently recruiting?
Yes, NCT05174286 is actively recruiting participants. Contact the research team at lam2160@cumc.columbia.edu for enrollment information.
Where is the NCT05174286 trial being conducted?
This trial is being conducted at New York, United States.
Who is sponsoring the NCT05174286 clinical trial?
NCT05174286 is sponsored by Columbia University. The principal investigator is Olajide A. Williams, MD, MS at Columbia University. The trial plans to enroll 880 participants.
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