NCT04312269 Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke
| NCT ID | NCT04312269 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Northwestern University |
| Condition | Stroke |
| Study Type | INTERVENTIONAL |
| Enrollment | 70 participants |
| Start Date | 2020-02-25 |
| Primary Completion | 2027-01-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 70 participants in total. It began in 2020-02-25 with a primary completion date of 2027-01-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study will examine the combination of myoelectric computer interface (MyoCI) training with targeted memory reactivation (TMR) in chronic stroke survivors. The study aims to determine whether this training-plus-sleep combination will generalize to improve arm motor function over an extended training protocol in stroke survivors.
Eligibility Criteria
Inclusion Criteria: * Age at enrollment is 21 or older * Hemiparesis from first ever stroke affecting arm movement at least 6 months prior to screening * Severe to moderate motor impairment (FMA-UE of 7-40) * At least some voluntary shoulder and elbow muscle activation Exclusion Criteria: * Inability to follow instructions of the MyoCI task * Visual impairment (such as hemianopia) preventing full view of screen * Anesthesia or neglect in the affected arm, or visual hemineglect (score of 2 on the NIH Stroke Scale Extinction and Inattention subtest) * Participation in another study on the affected arm within 6 weeks of enrollment or any pharmacological study * Inability to understand or follow commands in English due to aphasia or other reason * Diffuse or multifocal infarcts in both hemispheres * Substantial arm pain preventing participation for 90 minutes a day * Spasticity treatment (pharmacological or Botox) within last 3 months * Ferromagnetic implants that are MRI incompatible
Contact & Investigator
Marc W Slutzky, MD/PhD
PRINCIPAL INVESTIGATOR
Northwestern University
Frequently Asked Questions
Who can join the NCT04312269 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, up to 100 Years, studying Stroke. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04312269 currently recruiting?
Yes, NCT04312269 is actively recruiting participants. Contact the research team at mslutzky@northwestern.edu for enrollment information.
Where is the NCT04312269 trial being conducted?
This trial is being conducted at Chicago, United States.
Who is sponsoring the NCT04312269 clinical trial?
NCT04312269 is sponsored by Northwestern University. The principal investigator is Marc W Slutzky, MD/PhD at Northwestern University. The trial plans to enroll 70 participants.
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