Combined Treatment of Patients With Soft Tissue Sarcoma Including Preoperative Stereotactic Radiation Therapy and Postoperative Conformal Radiation Therapy
Trial Parameters
Brief Summary
Combined treatment of soft tissue sarcoma includes 3 steps: 1. step - preoperative stereotactic radiation therapy in hypofractionation mode 2. step - operation 3. step - postoperative conformal radiation therapy in normofractionation mode
Eligibility Criteria
Inclusion Criteria: * morphologically verified diagnosis of soft tissue sarcoma * first diagnosed tumor process * ability to perform radical surgery * signed informed consent * indications for stereotactic and conformal radiation therapy * no contraindications for radiation and surgical treatment Exclusion Criteria: * previous radiation treatment * acute infection * pregnancy, lactation * recurrent tumor * refuse to sign informed consent * conditions that can affect the outcome of treatment (immunodeficiency, tuberculosis, etc.) * tumor topography and volume that don't allow to perform stereotactic and conformal radiation therapy.