Combined Effects of INF and OEP in Patients With Diabetic Peripheral Neuropathy
Trial Parameters
Brief Summary
DPN often leads to balance issues, sensory deficits, and chronic pain, which can severely impact daily functioning and independence. INF therapy aims to improve nerve blood flow and alleviate neuropathic symptoms through manual techniques, while the Otago Exercise Program focuses on enhancing strength and balance to reduce fall risk. By comparing these two interventions, this study seeks to identify effective strategies that can improve balance, reduce pain, and enhance the quality of life for individuals suffering from DPN
Eligibility Criteria
Inclusion Criteria: * Age 50-75years * Both male and female patients will be included in the study * Patient with type 2 diabetes mellitus (diagnosed by the physician) * Patients with a score ≥ 4 on DN4 scale * Patients have a score on the Timed Up-and-Go (TUG) test of less than 15 s * Able to walk at least 10 meters long Exclusion Criteria: * Patient with presence of any other systemic disease rather than diabetes such as end-stage renal failure, uncontrolled hypertension, severe dyslipidemia, chronic liver disease, autoimmune disease, advanced chronic obstructive pulmonary disease etc * Patients with documented active alcohol or drug misuse * Patient with total or partial amputation of lower extremities * Participants will be also excluded if they were morbidly obese or if pregnant (self-reported) * Patient with active inflammations or other inflammatory neuropathies including chronic inflammatory demyelinating polyneuropathy, proximal diabetic neuropathy, chemotherapy-induced periph