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Recruiting NCT03207854

NCT03207854 Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers

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Clinical Trial Summary
NCT ID NCT03207854
Status Recruiting
Phase
Sponsor University of Southern California
Condition Healthy Subject
Study Type OBSERVATIONAL
Enrollment 625 participants
Start Date 2017-04-12
Primary Completion 2026-12-31

Eligibility & Interventions

Sex All sexes
Min Age 19 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Biospecimen CollectionLaboratory Biomarker AnalysisQuestionnaire Administration

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 625 participants in total. It began in 2017-04-12 with a primary completion date of 2026-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This research trial collects and stores blood, tissue, and bone marrow specimens from patients with cancer or blood disorders, and healthy volunteers to study the immune system in a variety of different types of experiments, as well as associated clinical data as appropriate, focused on understanding mechanisms of immunotherapy.

Eligibility Criteria

Inclusion Criteria: * All patients known to have cancer, an immune-mediated hematologic diagnosis, or a healthy normal volunteer * Definition of immune-mediated hematologic diagnosis: diagnoses for which immune dysfunction and/or immune system directed therapy (eg. aplastic anemia, autoimmune hemolytic anemia, immune thrombocytopenic purpura \[ITP\], etc.) are involved * Definition of healthy normal volunteer: persons lacking diagnoses of any type of cancer, diabetes, cardiovascular diseases, non-hematologic autoimmune disease (eg. systemic lupus erythematosus \[SLE\], rheumatoid arthritis \[RA\], Crohn's disease) and not taking any immunosuppressive medications * Patients must have been seen in the Norris Hospital and outpatient clinics, or the Los Angeles County (LAC)-University of Southern California (USC) Medical Center or outpatient clinics; healthy volunteers can be recruited without any physician visit appointments since their labs are strictly for clinical research and not for personal health issues unrelated to the project Exclusion Criteria: * Unable to give informed consent to specimen collection * Known human immunodeficiency virus (HIV) positive status * Persons taking any type of immunosuppressive medication are excluded from participating as healthy normal volunteers * Any patient for whom specimen collection is judged to be unsafe (for example, for patients unable to establish venous access)

Contact & Investigator

Central Contact

Arta Zenunovic

✉ Arta.zenunovic@med.usc.edu

📞 323-442 7828

Principal Investigator

Casey O'Connell, MD

PRINCIPAL INVESTIGATOR

University of Southern California

Frequently Asked Questions

Who can join the NCT03207854 clinical trial?

This trial is open to participants of all sexes, aged 19 Years or older, studying Healthy Subject. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT03207854 currently recruiting?

Yes, NCT03207854 is actively recruiting participants. Contact the research team at Arta.zenunovic@med.usc.edu for enrollment information.

Where is the NCT03207854 trial being conducted?

This trial is being conducted at Los Angeles, United States.

Who is sponsoring the NCT03207854 clinical trial?

NCT03207854 is sponsored by University of Southern California. The principal investigator is Casey O'Connell, MD at University of Southern California. The trial plans to enroll 625 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology