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RecruitingNCT03207854

Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers

◆ AI Clinical Summary
Plain-language summary for patients

Trial Parameters

ConditionHealthy Subject
SponsorUniversity of Southern California
Study TypeOBSERVATIONAL
PhaseN/A
Enrollment625
SexALL
Min Age19 Years
Max AgeN/A
Start Date2017-04-12
Completion2026-12-31
Interventions
Biospecimen CollectionLaboratory Biomarker AnalysisQuestionnaire Administration

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Brief Summary

This research trial collects and stores blood, tissue, and bone marrow specimens from patients with cancer or blood disorders, and healthy volunteers to study the immune system in a variety of different types of experiments, as well as associated clinical data as appropriate, focused on understanding mechanisms of immunotherapy.

Eligibility Criteria

Inclusion Criteria: * All patients known to have cancer, an immune-mediated hematologic diagnosis, or a healthy normal volunteer * Definition of immune-mediated hematologic diagnosis: diagnoses for which immune dysfunction and/or immune system directed therapy (eg. aplastic anemia, autoimmune hemolytic anemia, immune thrombocytopenic purpura \[ITP\], etc.) are involved * Definition of healthy normal volunteer: persons lacking diagnoses of any type of cancer, diabetes, cardiovascular diseases, non-hematologic autoimmune disease (eg. systemic lupus erythematosus \[SLE\], rheumatoid arthritis \[RA\], Crohn's disease) and not taking any immunosuppressive medications * Patients must have been seen in the Norris Hospital and outpatient clinics, or the Los Angeles County (LAC)-University of Southern California (USC) Medical Center or outpatient clinics; healthy volunteers can be recruited without any physician visit appointments since their labs are strictly for clinical research and not for

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