NCT00442195 Collection and Analysis of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers
| NCT ID | NCT00442195 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National Heart, Lung, and Blood Institute (NHLBI) |
| Condition | Healthy Volunteers |
| Study Type | OBSERVATIONAL |
| Enrollment | 1,000 participants |
| Start Date | 2007-03-03 |
| Primary Completion | — |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 1,000 participants in total. It began in 2007-03-03.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The Hematology Branch of the National Heart, Lung, and Blood Institute is doing a variety of laboratory research experiments that require blood and tissue samples from healthy volunteers. This protocol provides a mechanism for collecting these tissue samples. Research includes studies of normal and abnormal formation of blood cells, viral blood diseases, the role of the immune system in marrow failure and genetic risk factors for aplastic anemia. Healthy normal volunteers 8 years of age and older may be eligible for this study. Samples are collected as follows: * Blood samples: Participants 8 years of age and older donate up to 4 tablespoons of blood, which is obtained from a needle placed in an arm vein. * Participants 8 years of age and older donate a buccal mucosa sample (cells from the inside of the cheek). The inside of the cheek is scraped gently with a nylon brush. * Participants 18 years of age and older donate a bone marrow sample. The bone marrow is obtained from the hip bone. The skin over the area is wiped clean with alcohol and iodine, and then a local anesthetic is injected under the skin and also into the bone. When the area is numb, a bone marrow aspiration needle is introduced through the bone surface into the marrow. The marrow cells are collected using a syringe connected to the needle.
Eligibility Criteria
* INCLUSION CRITERIA: Self-declared healthy volunteer (for blood and buccal mucosa sample donors). Be healthy, as determined by Principal Investigator or designee based on recent (\<3 months) history, physical and laboratory results (for bone marrow and skin tissue sample donors). \<TAB\>\<TAB\>\<TAB\>\<TAB\>\<TAB\> Age 8 years and older (no upper limit) for blood and buccal mucosa sampling. OR Ages 18 years or older (no upper limit) for bone marrow or skin tissue sampling. EXCLUSION CRITERIA: Unable to comprehend the investigational nature of the protocol participation. CBC determined outside expected normal ranges for the subject (bone marrow and skin tissue donors only). Pregnancy Age less than 18 years for skin tissue sampling, bone marrow aspirate and biopsy. Off campus volunteers for skin tissue sampling bone marrow aspirate and biopsy.
Contact & Investigator
Neal S Young, M.D.
PRINCIPAL INVESTIGATOR
National Heart, Lung, and Blood Institute (NHLBI)
Frequently Asked Questions
Who can join the NCT00442195 clinical trial?
This trial is open to participants of all sexes, aged 8 Years or older, up to 99 Years, studying Healthy Volunteers. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT00442195 currently recruiting?
Yes, NCT00442195 is actively recruiting participants. Contact the research team at ccopr@nih.gov for enrollment information.
Where is the NCT00442195 trial being conducted?
This trial is being conducted at Bethesda, United States.
Who is sponsoring the NCT00442195 clinical trial?
NCT00442195 is sponsored by National Heart, Lung, and Blood Institute (NHLBI). The principal investigator is Neal S Young, M.D. at National Heart, Lung, and Blood Institute (NHLBI). The trial plans to enroll 1,000 participants.