Recruiting Phase 2 NCT05336201

Cognitive Remediation Intervention to Prepare for Transition of Care

Trial Parameters

Condition Sickle Cell Disease

Sponsor University of Alabama at Birmingham

Study Type INTERVENTIONAL

Phase Phase 2

Enrollment 120

Sex ALL

Min Age 10 Years

Max Age 18 Years

Start Date 2022-07-01

Completion 2026-09-30

All Conditions

Sickle Cell Disease Cognitive Impairment Adolescent Behavior Self Efficacy Health-Related Behavior Coping Skills

Interventions

CREADY (Cognitive-Remediation of Executive and Adaptive Deficits in Youth)

Brief Summary

Randomized Controlled Trial (RTC) testing the efficacy of a telehealth adaptation of the Cognitive-Remediation of Executive and Adaptive Deficits in Youth (C-READY) intervention to prepare adolescents with sickle cell disease for transition of care.

Eligibility Criteria

Inclusion Criteria: * Diagnosis of SCD (all genotypes) * Active follow-up at Children's of Alabama Hospital * Ages 10-18 * English-speaking Exclusion Criteria: * History of seizures or overt stroke * History of Intellectual Disability or Autism Spectrum Disorder * Inability to participate in the MRI scan, such as metal implants, neurostimulators, claustrophobia * Currently on psychotropic medications

Related Trials

NCT03976180

High-flow Oxygen for Vaso-occlusive Pain Crisis

View Trial →

NCT06385886

Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease

View Trial →

NCT07246265

Morphine Clearance and Glomerular Filtration in Sickle Cell Patients in Crisis in Intensive Care

View Trial →

VIEW ON CLINICALTRIALS.GOV ↗ MORE SICKLE CELL DISEASE TRIALS