NCT04938362 Cognitive Function and Fatigue After Brain Abscess
| NCT ID | NCT04938362 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Oslo |
| Condition | Brain Abscess |
| Study Type | OBSERVATIONAL |
| Enrollment | 50 participants |
| Start Date | 2020-01-01 |
| Primary Completion | 2030-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 50 participants in total. It began in 2020-01-01 with a primary completion date of 2030-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Brain abscess is a focal bacterial or fungal infection of the brain. Treatment is neurosurgical drainage of pus followed by long-term antibiotic treatment. In spite of successful treatment of the infection, long-term cognitive problems or mental fatigue may ensue. The reason for this dysfunction may be a continuing inflammatory state or damage to brain tissue caused by the abscess. The investigators will evaluate these possibilities with the use of \[18F\]deoxyglucose-positron emission tomography (FDG-PET) and electroencephalography (EEG) in patients who have been treated for brain abscess and who experience cognitive problems and/or fatigue. FDG-PET may identify both inflammation and altered neuronal activity (the latter indicating damage to brain tissue), and EEG may identify altered neuronal activity, including changes in neuronal network activity.
Eligibility Criteria
Inclusion criteria: • Patients who have completed treatment for brain abscess and who agree to participate. Exclusion criteria: * Patients who cannot undergo neuropsychological investigation due to unconsciousness * Patients who cannot undergo neuropsychological investigation, being mentally too ill * Patients who suffer from dementia * Patients who cannot undergo FDG-PET due to claustrophobia * Patients who cannot undergo EEG due to panic attacks * Age under 16.
Contact & Investigator
Bjørnar Hassel, MD, PhD
PRINCIPAL INVESTIGATOR
University of Oslo
Frequently Asked Questions
Who can join the NCT04938362 clinical trial?
This trial is open to participants of all sexes, aged 16 Years or older, studying Brain Abscess. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04938362 currently recruiting?
Yes, NCT04938362 is actively recruiting participants. Contact the research team at pedutn@ous-hf.no for enrollment information.
Where is the NCT04938362 trial being conducted?
This trial is being conducted at Oslo, Norway.
Who is sponsoring the NCT04938362 clinical trial?
NCT04938362 is sponsored by University of Oslo. The principal investigator is Bjørnar Hassel, MD, PhD at University of Oslo. The trial plans to enroll 50 participants.